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Merck

SAB4502013

Sigma-Aldrich

Anti-ENOS antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Constitutive NOS, EC-NOS, ECNOS, Endothelial NOS, cNOS

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 133 kDa

Speziesreaktivität

human, rat, mouse

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:40000
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... NOS3(4846)

Allgemeine Beschreibung

Anti-ENOS Antibody detects endogenous levels of total ENOS protein.
The ENOS (endothelial nitric oxide synthase) gene is mapped to human chromosome 7q36.1. ENOS is expressed predominantly in the endothelial cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human eNOS.

Immunogen Range: 581-630

Anwendung

Anti-ENOS antibody produced in rabbit has been used in SDS-PAGE and western blotting.

Biochem./physiol. Wirkung

ENOS (endothelial nitric oxide synthase) is responsible for the production of nitric oxide. eNOS is known to stimulate vasodilation and regulate inflammation and myocyte function. Impairment of endothelium-dependent vasodilatation that is observed in acute hyperglycaemia condition is due to suppression of ENOS. The gene might be involved in lipolysis. Variation in ENOS might lead to Henoch-Schönlein purpura. ENOS polymorphism affects the NO concentration in plasma.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

The role of the eNOS G894T and T-786C gene polymorphism in the development of ascites in cirrhosis.
Yildirim O
European Review for Medical and Pharmacological Sciences, 20(22), 4725-4730 (2016)
(-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: Potential role of endothelial nitric oxide synthase.
Ramirez-Sanchez I
Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease, 13(3), 201-210 (2016)
Mechanisms underlying the hypotensive and vasodilator effects of Ru(terpy)(bdq)NO](3+), a nitric oxide donor, differ between normotensive and spontaneously hypertensive rats.
Potje SR
European Journal of Pharmacology, 741, 222-229 (2014)
Association of Endothelial Nitric Oxide Synthase Gene Polymorphism with Susceptibility and Nephritis Development of Henoch-Schonlein Purpura in Chinese Han Children.
Wang A
Genetic Testing and Molecular Biomarkers, 21(6), 373-381 (2017)
Heat-shock protein 60 of Porphyromonas gingivalis may induce dysfunction of human umbilical endothelial cells via regulation of endothelial-nitric oxide synthase and vascular endothelial-cadherin.
Wu C
Biomedical Reports, 5(2), 243-247 (2016)

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