S0508

Sulfamonomethoxin

• Synonym(e): 4-Amino-N-(6-methoxy-4-pyrimidinyl)-benzolsulfonamid, 4-Methoxy-6-sulfanilamidopyrimidin, N¹-(6-Methoxy-4-pyrimidinyl)-sulfanilamid, SMM
• Empirische Formel (Hill-System): C₁₁H₁₂N₄O₃S
• CAS-Nummer: 1220-83-3
• Molekulargewicht: 280.30
• Beilstein: 621128
• MDL-Nummer: MFCD00063466
• UNSPSC-Code: 51283946
• PubChem Substanz-ID: 24899439
• NACRES: NA.85

Eigenschaften

• Form: powder
• Qualitätsniveau: 200
• Farbe: white to yellow-white
• Löslichkeit: methanol: soluble 10 mg/mL
• Wirkungsspektrum von Antibiotika: Gram-negative bacteria; Gram-positive bacteria; parasites
• Wirkungsweise: DNA synthesis | interferes; enzyme | inhibits
• SMILES String: COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1
• InChI: 1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)
• InChIKey: WMPXPUYPYQKQCX-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Chemical structure: sulfonamide

Anwendung

Sulfamonomethoxine is used to study degradation by Fe³O⁴ magnetic nanoparticles. It is used in blood kinetic studies and is used to study capsule formation of Bordetella bronchiseptica.

Biochem./physiol. Wirkung

Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H317,H319,H335
• P-Sätze: P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves