PZ0129

CP-380736

≥98% (HPLC)

• Synonym(e): 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• Empirische Formel (Hill-System): C₁₄H₁₈N₂O₅
• CAS-Nummer: 179688-29-0
• Molekulargewicht: 294.30
• MDL-Nummer: MFCD02678087
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 329823716
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: off-white to light tan
• Löslichkeit: DMSO: ≥10 mg/mL
• Lagertemp.: room temp
• SMILES String: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChIKey: PMQWTUWLIGJTQD-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Leistungsmerkmale und Vorteile

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable