C8221

Caffeic acid phenethyl ester

≥97% (HPLC), powder

• Synonym(e): CAPE
• Empirische Formel (Hill-System): C₁₇H₁₆O₄
• CAS-Nummer: 104594-70-9
• Molekulargewicht: 284.31
• MDL-Nummer: MFCD00866470
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 24278341
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Assay: ≥97% (HPLC)
• Form: powder
• Lagerbedingungen: protect from light
• Farbe: off-white
• Löslichkeit: ethyl acetate: 50 mg/mL; DMSO: soluble; ethanol: soluble
• Lagertemp.: −20°C
• SMILES String: Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O
• InChI: 1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
• InChIKey: SWUARLUWKZWEBQ-VQHVLOKHSA-N
• Angaben zum Gen: human ... NFKB2(4791)

Beschreibung

Anwendung

Caffeic acid phenethyl ester (CAPE) has been used to determine the effect of CAPE in hyperthyroidism, as a component of culture media to measure the cytotoxicity of breast cancer cell line MDA-MB-231, to study its effects on amiodarone-induced pulmonary fibrosis in rats.

Biochem./physiol. Wirkung

CAPE exhibits several properties such as anticarcinogenic, immunomodulatory activities, antioxidant, antiviral, anti-inflammatory, hypoglycaemic effect, cardioprotective and inhibits gastric secretion. It also has an inhibitory effect on fibroblasts growth factor type 2 (FGF-2), a tumor growth factor in breast cancer.

Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.

Leistungsmerkmale und Vorteile

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves