B2680

BMP4, human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Synonym(e): Bone Morphogenetic Protein 4 human, BMP-4
• MDL-Nummer: MFCD01867024
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Produktbezeichnung: Bone Morphogenetic Protein 4 human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
• Biologische Quelle: human
• Qualitätsniveau: 200
• Rekombinant: expressed in NSO cells
• Assay: >95% (SDS-PAGE)
• Form: lyophilized powder
• Wirksamkeit: 10-30 ng/mL ED₅₀
• Mol-Gew.: monomer calculated mol wt 13 kDa; ~22 kDa by SDS-PAGE
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: <1 EU/mg Endotoxin level (LAL test)
• UniProt-Hinterlegungsnummer: P12644
• Lagertemp.: −20°C
• Angaben zum Gen: human ... BMP4(652)

Beschreibung

Biochem./physiol. Wirkung

Cellular responses to BMP-4 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF A by osteoblasts. Mature human and mouse BMP-4 demonstrates 98% and 100% homology, respectively, to mature rat BMP-4.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 50 μg of bovine serum albumin per 1 μg of cytokine.

Hinweis zur Analyse

The biological activity is measured by its ability to induce alkaline phosphatase production by C2C12 myoblasts.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable