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01480

Sigma-Aldrich

Acetylthiocholiniodid

≥99.0% (AT)

Synonym(e):

(2-Mercaptoethyl)trimethylammonium iodide acetate

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About This Item

Lineare Formel:
CH3COSCH2CH2N(CH3)3I
CAS-Nummer:
1866-15-5
Molekulargewicht:
289.18
Beilstein:
3916578
EG-Nummer:
217-474-1
MDL-Nummer:
MFCD00011819
UNSPSC-Code:
12352204
PubChem Substanz-ID:
329747298
NACRES:
NA.83

Qualitätsniveau

100

Assay

≥99.0% (AT)

Glührückstand

≤0.05%

mp (Schmelzpunkt)

205-210 °C (lit.)
205-210 °C

Löslichkeit

H2O: 0.1 g/mL, clear, colorless

Lagertemp.

2-8°C

SMILES String

[I-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChIKey

NTBLZMAMTZXLBP-UHFFFAOYSA-M

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Anwendung

Acetylthiocholine iodide has been used as a substrate to determine anticholinesterase activity.
Substrat für die kolorimetrische Bestimmung der Acetylcholinesterase-Aktivität

Substrate

Acetylcholinesterase-Substrat und Agonist für nikotinische Acetylcholinrezeptoren.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301 + H311

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Cell death & disease, 6, e1685-e1685 (2015-03-15)
Proliferation, differentiation and death of ovarian cells ensure orderly functioning of the female gonad during the reproductive phase, which ultimately ends with menopause in women. These processes are regulated by several mechanisms, including local signaling via neurotransmitters. Previous studies showed
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Bioorganic & medicinal chemistry, 23(16), 5156-5167 (2015-02-14)
Dual submicromolar trypanocidal-antiplasmodial compounds have been identified by screening and chemical synthesis of 4-aminoquinoline-based heterodimeric compounds of three different structural classes. In Trypanosoma brucei, inhibition of the enzyme trypanothione reductase seems to be involved in the potent trypanocidal activity of
Belgin Sever et al.
International journal of biological macromolecules, 163, 1970-1988 (2020-09-16)
Alzheimer's disease (AD) is a complex, predominant, and progressive form of dementia. The treatment of AD alters depending on the cognitive and behavioral symptoms. The utility of cholinergic replacement by acetylcholinesterase (AChE) inhibitors in AD treatment has been well-documented so
Zrinka Kovarik et al.
Chemical research in toxicology, 28(5), 1036-1044 (2015-04-04)
Exposure to the nerve agent soman is difficult to treat due to the rapid dealkylation of the soman-acetylcholinesterase (AChE) conjugate known as aging. Oxime antidotes commonly used to reactivate organophosphate inhibited AChE are ineffective against soman, while the efficacy of
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