SMB01345

N-Methyl-2-pyridone-5-carboxamide

• Synonym(e): 1,6-Dihydro-1-methyl-6 -oxonicotinamide, 1-Methyl-5-carboxylamide-2-pyridone, 2-Py, 2PY, 3-Carbamoyl-1-methyl-6-pyridone, N¹-Methyl-2-pyridone-5-carboxamide, Me2PY, Met2PY, Nedifloramide, Nudifloramide
• Empirische Formel (Hill-System): C₇H₈N₂O₂
• CAS-Nummer: 701-44-0
• Molekulargewicht: 152.15
• MDL-Nummer: MFCD00457283
• NACRES: NA.77

Eigenschaften

• Assay: ≥95% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• mp (Schmelzpunkt): 210—21.5 °C
• InChI: 1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)
• InChIKey: JLQSXXWTCJPCBC-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

N-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Increased serum 2PY concentrations are observed in chronic renal failure (CRF) patients, which along with the deterioration of kidney function and its toxic properties (significant inhibition of PARP-1), suggests that 2PY is an uremic toxin.

Anwendung

Metabolomics research

Sonstige Hinweise

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable