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Merck

R7774

Sigma-Aldrich

Riboflavin 5′-phosphate sodium salt hydrate

meets USP testing specifications

Synonym(e):

Flavin Mononucleotide

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About This Item

Empirische Formel (Hill-System):
C17H20N4NaO9P · xH2O
Molekulargewicht:
478.33 (anhydrous basis)
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352205
eCl@ss:
34058005
PubChem Substanz-ID:
NACRES:
NA.21

Agentur

USP/NF
meets USP testing specifications

Qualitätsniveau

Assay

73.0-79.0% dry basis (BASED ON % RIBOFLAVIN)

Form

powder

Anwendung(en)

pharmaceutical (small molecule)

Lagertemp.

−20°C

SMILES String

O.[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C

InChI

1S/C17H21N4O9P.Na.H2O/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);;1H2/q;+1;/p-1/t11-,12+,14-;;/m0../s1

InChIKey

BHRVCJBIICJWTH-APQIITSESA-M

Allgemeine Beschreibung

Riboflavin 5′-phosphate (flavin mononucleotide (FMN)) is a vitamin B12 derivative, containing isoalloxazine ring system.

Anwendung

Riboflavin 5′-phosphate sodium salt hydrate has been used:
  • as a photosensitizing agent to assess in vitro efficacy of photodynamic therapy (PDT) on fungi
  • to evaluate its in vivo delivery in rat corneas
  • as a component in Vitamin and growth factor stock mix

Biochem./physiol. Wirkung

Riboflavin 5′-phosphate (flavin mononucleotide (FMN)) acts as a coenzyme in intermediary metabolism. Phosphorylation of vitamin B12 by flavokinase yields FMN.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Riboflavin (vitamin B2)
Handbook of vitamins, 255-273 (2013)
Cell isolation and culture
WormBook: The Online Review of C. elegans Biology (2005)
Zhi Li et al.
Biochemical and biophysical research communications, 467(3), 503-508 (2015-10-11)
Desulfotomaculum reducens MI-1 is a Firmicute strain capable of reducing a variety of heavy metal ions and has a great potential in heavy metal bioremediation. We recently identified Dred_2421 as a potential iron reductase through proteomic study of D. reducens. The
Marta Castrillo et al.
Photochemistry and photobiology, 91(6), 1356-1367 (2015-07-29)
Proteins from the cryptochrome/photolyase family utilize UV-A, blue or even red light to achieve such diverse functions as repair of DNA lesions by photolyases and signaling by cryptochromes. DASH-type cryptochromes retained the ability to repair cyclobutane pyrimidine dimers (CPDs) in
Alejandro Arboleda et al.
American journal of ophthalmology, 158(1), 64-70 (2014-05-06)
To compare the in vitro effect of rose bengal and riboflavin as photosensitizing agents for photodynamic therapy (PDT) on fungal isolates that are common causes of fungal keratitis. Experimental study. Three isolates (Fusarium solani, Aspergillus fumigatus, Candida albicans) recovered from

Artikel

How riboflavin and othercell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of riboflavin.

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