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Merck

F8399

Sigma-Aldrich

Riboflavin 5′-monphosphate Natriumsalz Hydrat

≥95% (HPLC)

Synonym(e):

FMN

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About This Item

Empirische Formel (Hill-System):
C17H20N4O9P · xNa+ · yH2O
Molekulargewicht:
455.34 (anhydrous free acid basis)
EG-Nummer:
UNSPSC-Code:
41106305
eCl@ss:
34058005
NACRES:
NA.51

Qualitätsniveau

Assay

≥95% (HPLC)

Form

powder

Lagertemp.

−20°C

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Allgemeine Beschreibung

Riboflavin 5′-monophosphate (FMN) is highly soluble in water. Flavins are considered as blue-light absorbing dyes.

Anwendung

Riboflavin 5′-monophosphate (FMN) is used as a prosthetic group by oxidoreductase (one and two electron transfer) enzymes such as NADH dehydrogenases, nitric oxide synthases, and nitrilotriacetate monooxygenases. Riboflavin 5′-monophosphate is used as a substrate to study the specificity and kinetics of FMN phosphohydrolases. FMN is used to study molecular sensing based gene regulation by riboswitches.
Riboflavin 5′-monophosphate sodium salt hydrate has been used:
  • in the study to examine FMN (flavin mononucleotide) photo-reduction in aqueous solutions
  • to immobilize on titanium oxide modified carbon fibre to determine its electrochemical behavior
  • in flavin identification

Biochem./physiol. Wirkung

Riboflavin 5′-monophosphate (FMN) acts as a cofactor in flavoproteins and possess biological activity in enzymes and photoreceptors.

Angaben zur Herstellung

Prepared by the enzymatic hydrolysis of flavin adenine dinucleotide.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Delivery of Riboflavin-5?-Monophosphate Into the Cornea: Can Liposomes Provide Any Enhancement Effects?
Kandzija N and Khutoryanskiy VV
Journal of Pharmaceutical Sciences, 106(10), 3041-3049 (2017)
Electrochemical behaviour of FAD and FMN immobilised on TiO2 modified carbon fibres supported by ATR-IR spectroscopy of FMN on TiO2
Kubota LT, et al.
Bioelectrochemistry and bioenergetics, 47(1), 39-46 (1998)
Photo-induced reduction of flavin mononucleotide in aqueous solutions
Song SH, et al.
Chemical Physics, 332(1), 55-65 (2007)
Induction and catalytic properties of an intracellular NADH-dependent 1, 4-benzoquinone reductase from the brown-rot basidiomycete Gloeophyllum trabeum
Qi W and Jellison J
International Biodeterioration & Biodegradation, 54(1), 53-60 (2004)
Nathan J Baird et al.
RNA biology, 7(3), 328-332 (2010-05-12)
Riboswitches are structured mRNA elements involved in gene regulation that respond to the intracellular concentration of specific small molecules. Binding of their cognate ligand is thought to elicit a global conformational change of the riboswitch, in addition to modulating the

Artikel

How riboflavin and othercell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of riboflavin.

Learn about the four membrane-bound protein complexes that make up the electron transport chain metabolic pathway supplying energy as ATP for cellular respiration.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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