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Merck

N6522

Sigma-Aldrich

β-Nicotinamidadenin-Dinucleotid Hydrat

≥98%, BioUltra, from yeast

Synonym(e):

β-DPN, β-NAD, Coenzym 1, Cozymase, DPN, Diphosphopyridinnucleotid, NAD, Nadid

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About This Item

Empirische Formel (Hill-System):
C21H27N7O14P2 · xH2O
CAS-Nummer:
Molekulargewicht:
663.43 (anhydrous basis)
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
eCl@ss:
39200202
PubChem Substanz-ID:
NACRES:
NA.55

Biologische Quelle

yeast

Qualitätsniveau

Produktlinie

BioUltra

Assay

≥98%

Form

powder

Verunreinigungen

≤0.1% Insoluble matter

Farbe

white to off-white

Löslichkeit

H2O: 0.1 M, clear, colorless to faintly yellow

Anionenspuren

chloride (Cl-): ≤0.2%
sulfate (SO42-): ≤0.05%

Kationenspuren

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.001%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

Lagertemp.

−20°C

SMILES String

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChIKey

BAWFJGJZGIEFAR-NNYOXOHSSA-N

Angaben zum Gen

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Anwendung


  • Electrochemical Sensor Development: β-Nicotinamide adenine dinucleotide hydrate is utilized in the development of carbon nanomaterial-based electrochemical sensors and biosensors. These devices are designed for the sensitive detection of pharmaceutical and biological compounds, highlighting its crucial role in enhancing the sensitivity and specificity of biochemical assays (Adhikari et al., 2015).

Biochem./physiol. Wirkung

Elektronenakzeptor

Verpackung

abgefüllt nach Gewicht des Feststoffs

Sonstige Hinweise

Dies ist die übliche Form von NAD.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Ana P Gomes et al.
Cell, 155(7), 1624-1638 (2013-12-24)
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
Brian J North et al.
The EMBO journal, 33(13), 1438-1453 (2014-05-16)
Mice overexpressing the mitotic checkpoint kinase gene BubR1 live longer, whereas mice hypomorphic for BubR1 (BubR1(H/H)) live shorter and show signs of accelerated aging. As wild-type mice age, BubR1 levels decline in many tissues, a process that is proposed to
Teigo Asai et al.
Organic letters, 15(8), 2058-2061 (2013-04-13)
Graphiopsis chlorocephala was separated from the surface-sterilized healthy leaves of Paeonia lactiflora (Paeoniaceae) and cultivated with nicotinamide (an NAD(+)-dependent HDAC inhibitor). The culture conditions significantly enhanced secondary metabolite production in the fungus and led to the isolation of a structurally
Jeerus Sucharitakul et al.
The Journal of biological chemistry, 288(49), 35210-35221 (2013-10-17)
3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is an NADH-specific flavoprotein monooxygenase that catalyzes the para-hydroxylation of 3-hydroxybenzoate (3HB) to form 2,5-dihydroxybenzoate (2,5-DHB). Based on results from stopped-flow spectrophotometry, the reduced enzyme-3HB complex reacts with oxygen to form a C4a-peroxy
Christian Dölle et al.
The FEBS journal, 280(15), 3530-3541 (2013-04-27)
Mitochondrial metabolism is intimately connected to the universal coenzyme NAD. In addition to its role in redox reactions of energy transduction, NAD serves as substrate in regulatory reactions that lead to its degradation. Importantly, all types of the known NAD-consuming

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