G1522

Gentamicin

solution, suitable for hybridoma, BioReagent

• Synonym(e): Garamycin, Gentiomycin C
• CAS-Nummer: 1405-41-0
• MDL-Nummer: MFCD00270181
• UNSPSC-Code: 12352207
• eCl@ss: 42020823
• PubChem Substanz-ID: 329799845
• NACRES: NA.76

Eigenschaften

• product name: Gentamicin -Lösung, Hybri-Max^™, 0.1 μm filtered, 50 mg/mL gentamicin, BioReagent, suitable for hybridoma
• Qualität: Hybri-Max^™; Prepared in tissue culture grade water.
• Qualitätsniveau: 300
• Sterilität: 0.1 μm filtered
• Produktlinie: BioReagent
• Form: liquid
• Konzentration: 50 mg/mL gentamicin
• Methode(n): cell culture | hybridoma: suitable
• Verunreinigungen: endotoxin, tested
• Farbe: colorless to light yellow
• Dichte: 1.000 g/cm³
• Wirkungsspektrum von Antibiotika: Gram-negative bacteria; Gram-positive bacteria; mycoplasma
• Wirkungsweise: protein synthesis | interferes
• Lagertemp.: 2-8°C
• SMILES String: OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O
• InChI: 1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1
• InChIKey: RDEIXVOBVLKYNT-HDZPSJEVSA-N

Beschreibung

Allgemeine Beschreibung

Chemical structure: aminoglycoside

Anwendung

Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.

Biochem./physiol. Wirkung

Wirkungsweise: Gentamicin hemmt die Proteinsynthese, indem es sich an die 30S-Untereinheit des Ribosoms bindet.

Antimikrobielles Spektrum: Unter anderem gramnegative und grampositive Bakterien, einschließlich Stämmen, die gegen Tetracyclin, Chloramphenicol, Kanamycin und Colistin resistent sind, insbesondere die Stämme Pseudomonas, Proteus, Staphylococcus und Streptococcus.

Komponenten

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.

Vorsicht

The product is stable at 37° for 5 days and is stored at 2-8°C.

Rechtliche Hinweise

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H317,H334
• P-Sätze: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Gefahreneinstufungen: Resp. Sens. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable