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Merck

56601

Supelco

Icariin

analytical standard

Synonym(e):

4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnosid-7-glucosid

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About This Item

Empirische Formel (Hill-System):
C33H40O15
CAS-Nummer:
Molekulargewicht:
676.66
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Assay

≥95% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Format

neat

Lagertemp.

2-8°C

SMILES String

COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2

InChI

1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1

InChIKey

TZJALUIVHRYQQB-XLRXWWTNSA-N

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Allgemeine Beschreibung

Icariin is a major flavonoid isolated from Epimedium spp. leaves, used as a traditional Chinese medicine to nourish the kidney and reinforce yang.

Anwendung

Icariin has been used as a test material to investigate its, in vitro effect in promoting mouse hair follicle growth, which is assessed by vibrissae hair follicle (VHF) organ-culture model.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Flavonoid glucoside derived from the the Epimedium plant genus. This pharmacologically active constituent or its derivatives have been shown to enhance bone formation, modulate multidrug resistance, enhance neuronal viability, stimulate angiogenesis, and exhibit antioxidant activity.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Icariin promotes mouse hair follicle growth by increasing insulin?like growth factor 1 expression in dermal papillary cells.
Su SY, et al.
Clinical and Experimental Dermatology, 42(3), 287-294 (2017)
Transforming Growth Factors?Advances in Research and Application (2012)

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