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Merck

55016

Supelco

Theaflavin

analytical standard

Synonym(e):

3,4,6-Trihydroxy-1,8-bis-(3α,5,7-trihydroxy-2α-chromanyl)-5H-benzocyclohepten-5-on

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About This Item

Empirische Formel (Hill-System):
C29H24O12
CAS-Nummer:
Molekulargewicht:
564.49
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥90.0% (HPLC)

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

−20°C

SMILES String

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1C3=Cc4c(cc(O)c(O)c4C(=O)C(O)=C3)[C@H]5Oc6cc(O)cc(O)c6C[C@H]5O

InChI

1S/C29H24O12/c30-11-3-17(32)15-8-21(36)28(40-23(15)5-11)10-1-13-14(7-20(35)27(39)25(13)26(38)19(34)2-10)29-22(37)9-16-18(33)4-12(31)6-24(16)41-29/h1-7,21-22,28-33,35-37,39H,8-9H2,(H,34,38)/t21-,22-,28-,29-/m1/s1

InChIKey

IPMYMEWFZKHGAX-ZKSIBHASSA-N

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Allgemeine Beschreibung

Theaflavin is a polyphenol, naturally available in tea, which can mainly play a role in the inhibition of xanthine oxidase enzyme to yield uric acid. It can also find applications in reducing oxidative stress and can also act like scavengers of superoxide.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Xueli Cao et al.
Journal of separation science, 34(19), 2611-2617 (2011-09-08)
An improved type-J counter-current chromatography (CCC) planet centrifuge with two spiral tube columns (volume 2×15 mL, β value 0.3-0.7, tubing 0.8 mm id) was developed and evaluated for its retention ability of four typical different solvent systems including heptane-methanol (1:1
Jie Yang et al.
AIDS research and human retroviruses, 28(11), 1498-1508 (2012-08-08)
We previously demonstrated that a commercially available natural product preparation with high content (>90%) of theaflavin derivatives (TFmix) exhibited potent anti-HIV activities. Here we developed a TFmix gel formulation as a topical microbicide candidate. The effect of TFmix on the
Andrew G Mercader et al.
Current medicinal chemistry, 19(25), 4324-4347 (2012-07-27)
Flavonoids have shown anticarcinogenic activity in cancer cell lines, animal models, and some human studies. Quantitative structure-activity relationship (QSAR) models have become useful tools for identification of promising lead compounds in anticancer drug development. However, epidemiological and clinical studies are
A Anandhan et al.
Neuroscience, 218, 257-267 (2012-05-29)
Evidence from clinical and experimental studies indicates that degeneration of nigrostriatal dopaminergic neurons is a pathological hallmark of Parkinson's disease (PD). The present study was designed to investigate the neuroprotective potential of theaflavin (TF) on oxidative stress, monoamine transporters and
Suchismita Mohanty et al.
Frontiers in bioscience (Scholar edition), 4, 300-320 (2011-12-29)
With phytochemicals executing a plethora of anti-tumor mechanisms, targeting the 'guardian angel' p53 appears to be a critical strategy to energize the process of cancer therapeutics. Regulation of anti-tumor p53 functions by dietary plant polyphenols particularly black tea and its

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