04573

Thiamin -hydrochlorid

tested according to Ph. Eur.

• Synonym(e): Thiamio hydrochloridum, Aneurin -hydrochlorid, Vitamin B₁ -hydrochlorid
• Empirische Formel (Hill-System): C₁₂H₁₇ClN₄OS · HCl
• CAS-Nummer: 67-03-8
• Molekulargewicht: 337.27
• Beilstein: 3851771
• EG-Nummer: 200-641-8
• MDL-Nummer: MFCD00012780
• UNSPSC-Code: 12352209
• eCl@ss: 34058006
• PubChem Substanz-ID: 329747946
• NACRES: NA.26

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Agentur: USP/NF; tested according to Ph. Eur.
• Assay: 98.5-101.0% anhydrous basis
• Form: solid
• mp (Schmelzpunkt): 250 °C (dec.) (lit.)
• Löslichkeit: alcohol: soluble 1 gm in 100 ml (95%); alcohol: soluble 1 gm in 315 ml (Absolute); glycerol: soluble 1 gm in 18 ml; water: soluble 1 g/mL; benzene: insoluble; chloroform: insoluble; diethyl ether: insoluble; hexane: insoluble; methanol: very soluble; propylene glycol: soluble
• Lagertemp.: 2-8°C
• SMILES String: CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
• InChI: 1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
• InChIKey: DPJRMOMPQZCRJU-UHFFFAOYSA-M

Beschreibung

Anwendung

Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.

Biochem./physiol. Wirkung

Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.

Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B₁). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319
• P-Sätze: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)