Direkt zum Inhalt
Merck
Alle Fotos(5)

Key Documents

MAB16983Z

Sigma-Aldrich

Anti-Integrin α4 Antibody, clone P1H4, azide free

clone P1H4, Chemicon®, from mouse

Synonym(e):

CD49d, MAB16983

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(5)

About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

P1H4, monoclonal

Speziesreaktivität

human, primate

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_000632.3

UniProt-Hinterlegungsnummer

P11215

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ITGA4(3676)

Verwandte Kategorien

Spezifität

The involvement of integrins in vascular proliferation, adhesion, and wound repair and have been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits Monoclonal antibody MAB16983Z was produced by immunization with human T lymphocytes. The antibody is reactive with integrin alpha-4 from primate and human species.

Anwendung

Anti-Integrin α4 Antibody, clone P1H4, azide free is an antibody against Integrin α4 for use in ELISA, FC, IC, IH & IP.
Immunohistochemistry (preferred fixatives are acetone and alcohols)

Immunocytochemistry

Immunoprecipitation

FACS Analysis

ELISA

Radioimmunoassay

Biological Activity: MAB16983Z inhibits CS-1 and VCAM binding.

Optimal working dilutions must be determined by end user.

Physikalische Form

Format: Purified
Protein A Purified immunoglobulin in 0.01M PBS pH 7.1, 0.15M NaCl containing no preservatives.

Hinweis zur Analyse

Control
Widely expressed, Intestinal mucosa

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Sie haben nicht das passende Produkt gefunden?  

Probieren Sie unser Produkt-Auswahlhilfe. aus.

Empfehlung

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

O Jung et al.
Oncogenesis, 5, e202-e202 (2016-03-02)
Multiple myeloma arises when malignant plasma cells invade and form multiple tumors in the bone marrow. High levels of heparanase (HPSE) correlate with poor prognosis in myeloma patients. A likely target of the enzyme is the heparan sulfate (HS) proteoglycan
Arti V Shinde et al.
Matrix biology : journal of the International Society for Matrix Biology, 41, 26-35 (2014-11-30)
Prompt deposition of fibronectin-rich extracellular matrix is a critical feature of normal development and the host-response to injury. Fibronectin isoforms that include the EDA and EDB domains are prominent in these fibronectin matrices. We now report using human dermal fibroblast
Neisseria gonorrhoeae-induced transactivation of EGFR enhances gonococcal invasion.
Swanson KV, Griffiss JM, Edwards VL, Stein DC, Song W.
Cellular Microbiology null
N Assa-Munt et al.
Biochemistry, 40(8), 2373-2378 (2001-05-01)
The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the activities of the matrix proteins. Depending on the context of the RGD sequence, an RGD-containing peptide may
Neisseria meningitidis adhesin NadA targets beta1 integrins: functional similarity to Yersinia invasin.
Nagele, V; Heesemann, J; Schielke, S; Jimenez-Soto, LF; Kurzai, O; Ackermann, N
The Journal of Biological Chemistry null
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.