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Key Documents

04-298

Sigma-Aldrich

Anti-IGF1 Receptor (CT) Antibody, clone 7G11

clone 7G11, Upstate®, from mouse

Synonym(e):

insulin-like growth factor 1

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

7G11, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Upstate®

Methode(n)

ELISA: suitable
western blot: suitable

Isotyp

IgG1

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... IGF1(3479)

Spezifität

Recognizes C-terminus of IGF1 receptor

Immunogen

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of the C-terminus in human IGF1

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Insulin-/stoffwechselassoziierte Signalübertragung
Anti-IGF1 Receptor (C-terminus) Antibody, clone 7G11 detects level of IGF1 Receptor (C-terminus) & has been published & validated for use in ELISA & WB.

Qualität

Routinely evaluated by immunoblot.

Zielbeschreibung

90 kDa

Physikalische Form

Subsequent thiophilic adsorption and size exclusion chromatography
100 &mciro;g of purified mouse monoclonal IgG lyophilized in 2X PBS containing 0.09% sodium azide, PEG, and sucrose
Format: Purified

Lagerung und Haltbarkeit

2 years at -20°C from date of shipment. Reconstitute prior to use. Reconstitute with 1 mL H2O for 15 min at room temperature. Reconstituted aliquots should be stored frozen at -80°C. Thawed aliquots may be stored at 4°C for up to 3 months. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Hinweis zur Analyse

Control
Includes untreated A431 lysate as a positive control.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

M Wallander et al.
Diabetologia, 49(10), 2247-2255 (2006-09-07)
Low levels of IGF-I are associated with increased risk of cardiovascular disease and type 2 diabetes. The aim of this study was to investigate the IGF-I system in patients with acute myocardial infarction (AMI) without previously known diabetes. One hundred
Thomas Thum et al.
Circulation research, 100(3), 434-443 (2007-01-20)
Aging is associated with an increased risk for atherosclerosis. A possible cause is low numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair damaged vascular walls. We hypothesized that decreased levels of insulin-like growth factor-1 (IGF-1) during age
Shuhua Chen et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(4), 1813-1824 (2020-07-08)
Previous studies demonstrated that the endogenous neurosteroid allopregnanolone (Allo) promotes regeneration of rodent and human neural progenitor/neural stem cells (NSCs) in vitro and in vivo, and restores neurogenesis and cognitive function in the male triple transgenic mouse model of Alzheimer's

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