T-058

Tapentadol -hydrochlorid -Lösung

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(e): Tapentadol -hydrochlorid -Lösung
• Empirische Formel (Hill-System): C₁₄H₂₃NO · HCl
• CAS-Nummer: 175591-09-0
• Molekulargewicht: 257.80
• EG-Nummer: 200-659-6
• MDL-Nummer: MFCD00944992
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329826275
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Qualitätsniveau: 300
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• Konzentration: 1.0 mg/mL in methanol (as free base)
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): forensics and toxicology
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: Cl.CC[C@H]([C@@H](C)CN(C)C)c1cccc(O)c1
• InChI: 1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14+;/m0./s1
• InChIKey: ZELFLGGRLLOERW-YECZQDJWSA-N
• Angaben zum Gen: human ... OPRM1(4988) , SLC6A2(6530)

Beschreibung

Allgemeine Beschreibung

Tapentadol die erste Neuzulassung in den USA im Bereich zentral wirksamer Analgetika seit 25 Jahren. Diese Snap-N-Spike^® Referenzlösung eignet sich für viele LC/MS- oder GC/MS-Anwendungen, u. a. in der forensischen Analytik, pharmazeutischen Analytik, Überwachung von Analgesikaverordnungen und Urin-Drogenkontrolle.

Anwendung

• Extended-Release Formulation for Chronic Pain: Extended-release formulations of Tapentadol hydrochloride are developed to provide sustained pain relief for chronic conditions. This formulation reduces the frequency of dosing and enhances patient compliance, offering consistent pain management (Faria et al., 2017).
• Pharmaceutical Quality Control and Research: High-purity Tapentadol hydrochloride solutions are essential in pharmaceutical research and quality control. These solutions are used for the calibration of analytical instruments and ensuring the consistency and safety of pharmaceutical products (Fejos et al., 2014).
• Transdermal Delivery Systems: Innovative research has developed PEGylated ultra-deformable transferosomes for the transdermal delivery of Tapentadol, improving its bioavailability and analgesic activity. This method offers a non-invasive alternative for pain management (Deng et al., 2022).
• Innovative Pain Management Solutions: Research on new delivery methods, such as intranasal administration using chitosan nanoparticles, aims to enhance the therapeutic potential and patient compliance of Tapentadol hydrochloride solution for pain management (Javia & Thakkar, 2017).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes,Central nervous system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup