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P3654

Sigma-Aldrich

Prazepam

Synonym(e):

7-Chlor-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-on

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About This Item

Empirische Formel (Hill-System):
C19H17ClN2O
CAS-Nummer:
2955-38-6
Molekulargewicht:
324.80
EG-Nummer:
220-975-8
MDL-Nummer:
MFCD00057905
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24898436
NACRES:
NA.77

Form

solid

Qualitätsniveau

200

Arzneimittelkontrolle

USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

SMILES String

Clc1ccc2N(CC3CC3)C(=O)CN=C(c4ccccc4)c2c1

InChI

1S/C19H17ClN2O/c20-15-8-9-17-16(10-15)19(14-4-2-1-3-5-14)21-11-18(23)22(17)12-13-6-7-13/h1-5,8-10,13H,6-7,11-12H2

InChIKey

MWQCHHACWWAQLJ-UHFFFAOYSA-N

Angaben zum Gen

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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Biochem./physiol. Wirkung

Anxiolytic

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H336

Gefahreneinstufungen

STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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F Lapostolle et al.
Journal of toxicology. Clinical toxicology, 38(5), 477-482 (2000-09-12)
The radiopacity of ingested substances may serve as a clue to the presence of particular compounds, as this characteristic varies considerably among medications and household products. Tablet conglomerations are also variably radiopaque. We report 4 cases of clomipramine poisoning associated
X H Chen et al.
Journal of chromatography, 617(1), 147-151 (1993-07-23)
The lot-to-lot reproducibilities of Bond Elut Certify and Clean Screen DAU columns are described. The recoveries of five test drugs obtained from twelve lots of Bond Elut Certify columns ranged from 84 to 104% with standard deviations of less than
H L Tai et al.
Clinical biochemistry, 26(3), 165-171 (1993-06-01)
A simple, rapid high-pressure liquid chromatography (HPLC) method was developed for detecting and quantifying benzodiazepines in serum. Seven major benzodiazepines were extracted from spiked serum samples using solid-phase extraction with prazepam as the internal standard. The eluted drugs were then
François-Ludovic Sauvage et al.
Journal of separation science, 32(18), 3074-3083 (2009-08-22)
LC coupled to single (LC-MS) and tandem (LC-MS/MS) mass spectrometry is recognized as the most powerful analytical tools for metabolic studies in drug discovery. In this article, we describe five cases illustrating the utility of screening xenobiotic metabolites in routine
H A Archontaki et al.
Journal of pharmaceutical and biomedical analysis, 17(4-5), 739-750 (1998-07-31)
A reversed-phase HPLC method was developed for the kinetic investigation of the acidic hydrolysis of prazepam which was carried out in hydrochloric acid solutions of 0.01, 0.1 and 1.0 M. In addition, a fourth-order derivative method for monitoring the parent
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