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840033P

Avanti

14:0 PS

Avanti Research - A Croda Brand

Synonym(e):

1,2-ditetradecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DMPS; PS(14:0/14:0)

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About This Item

Empirische Formel (Hill-System):
C34H65NO10PNa
CAS-Nummer:
Molekulargewicht:
701.84
UNSPSC-Code:
51191904
NACRES:
NA.25

Beschreibung

1,2-dimyristoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 10 mg (840033P-10mg)
pkg of 1 × 200 mg (840033P-200mg)
pkg of 1 × 25 mg (840033P-25mg)

Hersteller/Markenname

Avanti Research - A Croda Brand

Lipid-Typ

phospholipids
cardiolipins

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C34H66NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-32(36)42-27-30(28-43-46(40,41)44-29-31(35)34(38)39)45-33(37)26-24-22-20-18-16-14-12-10-8-6-4-2;/h30-31H,3-29,35H2,1-2H3,(H,38,39)(H,40,41);/q;+1/p-1/t30-,31+;/m1./s1

InChIKey

QSHQBWBFNCFHLO-MFABWLECSA-M

Allgemeine Beschreibung

Phosphatidylserine (PS) is a retinal phospholipid, which carries long-chain highly unsaturated fatty acyl groups.

Anwendung

14:0 PS may be used as an internal standard for spiking serum lipid samples for liquid chromatography-mass spectroscopy analysis and as a component in the phospholipid monolayer to mimic model cancer cell membrane for the anticancer drug doxorubicin (DOx) interaction studies. It has been used in lipid binding assay to assess the binding of monoclonal antibodies (mAbs).

Biochem./physiol. Wirkung

Phosphatidylserine (PS) helps to activate protein kinase C (PKC). It may possess anti-inflammatory properties. PS is also known to participate in tyrosine hydroxylase activation. It is also involved in the uptake of Ca2+ and glucose.

Verpackung

5 mL Amber Glass Screw Cap Vial (840033P-10mg)
5 mL Amber Glass Screw Cap Vial (840033P-200mg)
5 mL Amber Glass Screw Cap Vial (840033P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

auch häufig zusammen mit diesem Produkt gekauft

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

B Fichtl et al.
Langmuir : the ACS journal of surfaces and colloids, 34(16), 4914-4919 (2018-04-04)
Currently, biological signaling is envisaged as a combination of activation and movement, triggered by local molecular interactions and molecular diffusion, respectively. However, here, we suggest that other fundamental physical mechanisms might play an at least equally important role. We have
Cognitive Effects of Nutraceuticals
Nutraceuticals, 29-48 (2016)
Regina Adão et al.
Biochimica et biophysica acta. Biomembranes, 1862(9), 183314-183314 (2020-04-19)
α-Synuclein (αsyn) is a cytosolic intrinsically disordered protein (IDP) known to fold into an α-helical structure when binding to membrane lipids, decreasing protein aggregation. Model membrane enable elucidation of factors critically affecting protein folding/aggregation, mostly using either small unilamellar vesicles
Jakub Suchodolski et al.
Yeast (Chichester, England), 37(1), 117-129 (2019-12-12)
Adherence of the fungus, Candida albicans, to biotic (e.g. human tissues) and abiotic (e.g. catheters) surfaces can lead to emergence of opportunistic infections in humans. The process of adhesion and further biofilm development depends, in part, on cell surface hydrophobicity
Paulina Perczyk et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183136-183136 (2019-11-22)
Soil fungi play an important role in the environment decomposing dead organic matter and degrading persistent organic pollutants (POP). The presence of hydrophobic POP in the soil and membrane-lytic substances excreted by competing microorganism to the soil solution is the

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