840038P

12:0 PS

1,2-dilauroyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

• Synonym(e): 1,2-didodecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DLPS; PS(12:0/12:0)
• Empirische Formel (Hill-System): C₃₀H₅₇NO₁₀PNa
• CAS-Nummer: 208757-51-1
• Molekulargewicht: 645.74
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 10 mg (840038P-10mg); pkg of 1 × 200 mg (840038P-200mg); pkg of 1 × 25 mg (840038P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 840038P
• Lipid-Typ: phospholipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C30H58NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-28(32)38-23-26(24-39-42(36,37)40-25-27(31)30(34)35)41-29(33)22-20-18-16-14-12-10-8-6-4-2;/h26-27H,3-25,31H2,1-2H3,(H,34,35)(H,36,37);/q;+1/p-1/t26-,27+;/m1./s1
• InChIKey: QBSSGICBQYAHPS-OUPRKWGVSA-M

Beschreibung

Allgemeine Beschreibung

Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.

Anwendung

12:0 PS may be used:

• in the preparation of large unilamellar vesicles (LUVs)
• as a standard to spike replicas of extracted lipid droplets and calibration curve generation for lipidomic analysis
• to study its effects on α-secretase activity

Biochem./physiol. Wirkung

Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.

Verpackung

5 mL Amber Glass Screw Cap Vial (840038P-10mg)

5 mL Amber Glass Screw Cap Vial (840038P-200mg)

5 mL Amber Glass Screw Cap Vial (840038P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids