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KITALYSIS-SM

Sigma-Aldrich

KitAlysis™ High-Throughput Suzuki-Miyaura Cross-Coupling Reaction Screening Kit - Pack of 4

Synonym(e):

Suzuki-Miyaura Cross-Coupling

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About This Item

UNSPSC-Code:
12161600
NACRES:
NA.22

Eignung der Reaktion

reaction type: Cross Couplings
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
core: palladium

Funktionelle Gruppe

phosphine

Anwendung

Screening kit for Suzuki-Miyaura cross-coupling reaction. Step-by-step user guide and a downloadable experimental excel sheets are provided in the below hyperlink.
Step-by-Step Guide for Suzuki-Miyaura Cross-Coupling Reaction Screening Kit
Downloadable experimental excel sheet

Each kit contains 4 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 1 (2 mL) ampule each of Toluene, THF, n-Butanol, DMAc, and aq. 1.5 M K3PO4.
  • 4 NEW KitAlysis 24-Well Reaction Block Replacement Films.
  • 4 substrate reaction vials with stir bars.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Leistungsmerkmale und Vorteile

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Rechtliche Hinweise

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Nur Kit-Komponenten

Produkt-Nr.
Beschreibung
  • SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules 1 EA

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB
  • 732117Pd-PEPPSI™-IPent catalyst, ≥95% 5 µmolSDB
  • 753009SPhos Pd G2 5 µmolSDB
  • 761311cataCXium® A Pd G2 5 µmolSDB
  • 763381XPhos Pd G3, 98%, 1:1 MTBE adduct 5 µmolSDB
  • 764175P(Cy3) Pd G3, 97% 5 µmolSDB
  • 764183APhos Pd G3, 97% 5 µmolSDB
  • 900522Toluene, anhydrous, ZerO2®, 99.8% 8 mLSDB
  • 900636Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9% 8 mLSDB
  • 9006391-Butanol, anhydrous, ZerO2®, 99.8% 8 mLSDB
  • 900634N,N-Dimethylacetamide, anhydrous, ZerO2®, 99.8% 8 mLSDB
  • Degassed Potassium phosphate tribasic solution 8 mL
  • Z118850Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mm 1 EASDB
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Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Zielorgane

Central nervous system, Respiratory system

Zusätzliche Gefahrenhinweise

EUH019

Lagerklassenschlüssel

3 - Flammable liquids

Flammpunkt (°F)

1.4 °F

Flammpunkt (°C)

-17 °C

Zulassungslistungen

Zulassungslistungen werden hauptsächlich für chemische Produkte erstellt. Für nicht-chemische Produkte können hier nur begrenzte Angaben gemacht werden. Kein Eintrag bedeutet, dass keine der Komponenten gelistet ist. Es liegt in der Verantwortung des Benutzers, die sichere und legale Verwendung des Produkts zu gewährleisten.

EU REACH Annex XVII (Restriction List)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Leider sind derzeit keine COAs für dieses Produkt online verfügbar.

Wenn Sie Hilfe benötigen, wenden Sie sich bitte an Kundensupport

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

High-Throughput Experimentation in Catalysis and Materials Science.
Gordillo A, et al.
Ullmann's Encyclopedia of Industrial Chemistry (2014)
Scientist-Led High-Throughput Experimentation (HTE) and Its Utility in Academia and Industry.
Schmink JR, et al.
Aldrichimica Acta, 46, 71-80 (2013)
Spencer D Dreher et al.
Journal of the American Chemical Society, 130(29), 9257-9259 (2008-06-28)
Microscale parallel experimentation was used to discover three catalyst systems capable of coupling secondary organotrifluoroborates with sterically and electronically demanding aryl chlorides and bromides. The ensuing results represent the first comprehensive study of alkylboron coupling to aryl chlorides and, in
Karl D Collins et al.
Nature chemistry, 6(10), 859-871 (2014-09-23)
New organic reactivity has often been discovered by happenstance. Several recent research efforts have attempted to leverage this to discover new reactions. In this Review, we attempt to unify reported approaches to reaction discovery on the basis of the practical

Artikel

Scale-Up Guide: Suzuki-Miyaura Cross-Coupling Reaction

All of the preformed catalysts used in the kit are air and moisture stable complexes in their commercially available form.

KitAlysis™ High-Throughput Screening Platform

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

KitAlysis™ Suzuki-Miyaura Cross-Coupling Reaction Screening Kit

Multiple tools have been created to ensure your success with kit set up. Start with the more detailed guide to ensure you are comfortable with all of the steps before using the quick guides on the excel worksheet. Remember that while the technique is new, it is still organic chemistry and so the steps will seem easy once you try just one kit. It is just a new way of approaching something you are already very good at.

KitAlysis High-Throughput Palladium Precatalyst Cross-Coupling Reaction Screening Kit

Materials Included in your KITALYSIS-24PD-2PK High-Throughput Screening Kit

Protokolle

Step-by-Step Guide for KitAlysis™ Suzuki-Miyaura Cross-Coupling Reaction Screening Kit

A step-by-step protocol guide for KitAlysis Suzuki-Miyaura Cross-Coupling Reaction Screening Kit.

Verwandter Inhalt

Reaction Design & Optimization

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

Reaktionsplanung & -optimierung

Die Planung und Optimierung chemischer Reaktionen in der organischen Synthese zielt darauf ab, Reaktionsparameter präzise zu ändern, um optimale Ergebnisse bei der Suche nach Synthesewegen zu Zielmolekülen zu erzielen.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.