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Merck

531480

Sigma-Aldrich

Fmoc-Ala-OH

95%, for peptide synthesis

Synonym(e):

N-(Fluorenyl-9-methoxycarbonyl)-L-alanin, Fmoc-L-alanin

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About This Item

Empirische Formel (Hill-System):
C18H17NO4
CAS-Nummer:
Molekulargewicht:
311.33
Beilstein:
2225975
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.26

Produktbezeichnung

Fmoc-Ala-OH, 95%

Assay

95%

Optische Aktivität

[α]20/D −18°, c = 1 in DMF

Eignung der Reaktion

reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis

mp (Schmelzpunkt)

147-153 °C (lit.)

Anwendung(en)

peptide synthesis

Funktionelle Gruppe

Fmoc
amine
carboxylic acid

Lagertemp.

2-8°C

SMILES String

C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1

InChIKey

QWXZOFZKSQXPDC-NSHDSACASA-N

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Allgemeine Beschreibung

Fmoc-Ala-OH also known as Fmoc-L-alanine, is a versatile reagent used in Fmoc solid-phase peptide synthesis.

Anwendung

Fmoc-Ala-OH is commonly used :
  • as a building block in the preparation of triazolopeptides , and azapeptides
  • in the synthesis of bis-cationic porphyrin peptides using the standard Fmoc solid-phase synthesis
  • to transform Mannich-adducts into α-halogenated amides without undergoing aziridination

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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