531413

2,2-Difluor-2-(fluorsulfonyl)essigsäure

97%

• Synonym(e): (Fluorosulfonyl)difluoroacetic acid
• Lineare Formel: FSO₂CF₂CO₂H
• CAS-Nummer: 1717-59-5
• Molekulargewicht: 178.09
• MDL-Nummer: MFCD01320807
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24877815
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Eignung der Reaktion: reaction type: click chemistry
• Brechungsindex: n20/D 1.36 (lit.)
• bp: 153 °C (lit.)
• Dichte: 1.723 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: carboxylic acid; fluoro
• SMILES String: OC(=O)C(F)(F)S(F)(=O)=O
• InChI: 1S/C2HF3O4S/c3-2(4,1(6)7)10(5,8)9/h(H,6,7)
• InChIKey: VYDQUABHDFWIIX-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2,2-Difluoro-2-(fluorosulfonyl)acetic acid reagent is employed as a difluorocarbene source for difluoromethylation of phenolic hydroxyl groups.

Anwendung

2,2-Difluoro-2-(fluorosulfonyl)acetic acid may be used in the following processes:

• Preparation of 1-difluoromethyl-2-oxo-1,2-dihydropyridine analogs by reacting with the corresponding 2-chloropyridines.
• Prepration of silyl fluorosulfonyldifluoroacetate as new highly efficient difluorocarbene reagent for cyclopropanation of alkenes.
• Regio- and stereoselective free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H300 + H310,H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P361 + P364 - P405
• Gefahreneinstufungen: Acute Tox. 2 Oral - Skin Corr. 1A
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 230.0 °F - closed cup
• Flammpunkt (°C): 110 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges