242705

2-Propansulfonylchlorid

97%

• Lineare Formel: (CH₃)₂CHSO₂Cl
• CAS-Nummer: 10147-37-2
• Molekulargewicht: 142.60
• Beilstein: 1747497
• EG-Nummer: 233-415-2
• MDL-Nummer: MFCD00007453
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24854579
• NACRES: NA.22

Eigenschaften

• Dampfdichte: 4 (vs air)
• Dampfdruck: 15.5 mmHg ( 25 °C)
• Assay: 97%
• Form: liquid
• Selbstzündungstemp.: 865 °F
• Brechungsindex: n20/D 1.453 (lit.)
• bp: 74-75 °C/19 mmHg (lit.)
• Dichte: 1.27 g/mL at 25 °C (lit.)
• SMILES String: CC(C)S(Cl)(=O)=O
• InChI: 1S/C3H7ClO2S/c1-3(2)7(4,5)6/h3H,1-2H3
• InChIKey: DRINJBFRTLBHNF-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

The solvolysis of 2-propanesulfonyl chloride by an addition-elimination (association-dissociation) pathway was studied.

Anwendung

2-Propanesulfonyl chloride (isopropylsulfonyl chloride) can be used as a reactant to prepare:

• 1-Isopropylsulfonyl-2-amine benzimidazole by reacting with 2-aminobenzimidazole via N-sulfonylation reaction in the presence of a base.
• Bis(isopropylsulfonyl)disulfide, a sulfurizing agent, used to synthesize phosphorothioate oligonucleotide analogs.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Gefahreneinstufungen: Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 186.8 °F - closed cup
• Flammpunkt (°C): 86 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter