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Sigma-Aldrich

Buttersäureamid

≥98.0% (T)

Synonym(e):

Amid C4

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About This Item

Lineare Formel:
CH3CH2CH2CONH2
CAS-Nummer:
541-35-5
Molekulargewicht:
87.12
Beilstein:
1361528
EG-Nummer:
208-776-4
MDL-Nummer:
MFCD00041894
UNSPSC-Code:
12352100
PubChem Substanz-ID:
57647787
NACRES:
NA.22

Assay

≥98.0% (T)

mp (Schmelzpunkt)

114-116 °C

Löslichkeit

alcohol: soluble(lit.)
diethyl ether: slightly soluble(lit.)
water: soluble(lit.)

SMILES String

CCCC(N)=O

InChI

1S/C4H9NO/c1-2-3-4(5)6/h2-3H2,1H3,(H2,5,6)

InChIKey

DNSISZSEWVHGLH-UHFFFAOYSA-N

Angaben zum Gen

rat ... Ggt1(116568)

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Anwendung

Butyramide was used in the synthesis of hydroxamic acids, electrorheological fluids and β-amodoorganotin compounds. It was used as substrate of (+)-γ-lactamase to develop a microreactor to study enzyme stability, activity, kinetics and substrate specificity.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Acetamid ≥99.0% (GC)

Sigma-Aldrich

00160

Acetamid

N-Methylacetamid ≥99%

Sigma-Aldrich

M26305

N-Methylacetamid

3-Chlor-1-Propanol 98%

Sigma-Aldrich

C46403

3-Chlor-1-Propanol

Benzamid 99%

Sigma-Aldrich

135828

Benzamid

Buttersäure ≥99%

Sigma-Aldrich

B103500

Buttersäure

Hongjian Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(5), 795-805 (2007-02-17)
2-{Butyryl-[2'-(4,5-dimethyl-isoxazol-3-ylsulfamoyl)-biphenyl-4-ylmethyl]-amino}-N-isopropyl-3-methyl-butyramide (BMS-1) is a potent dual acting angiotensin-1 and endothelin-A receptor antagonist. The compound was subject to rapid metabolic clearance in monkey and human liver microsomes and exhibited low systemic exposure and marked interanimal variability in cynomolgus monkeys after p.o.
P Rocchi et al.
Anticancer research, 18(2A), 1099-1103 (1998-06-06)
Butyric acid has been shown in vitro to produce cytodifferentiation of a wide variety of neoplastic cells. The potential clinical use of this compound as a therapeutic agent is limited by its rapid metabolism. This has led to the examination
B P O'Hara et al.
Protein engineering, 13(2), 129-132 (2000-03-10)
The AmiC protein in Pseudomonas aeruginosa is the negative regulator and ligand receptor for an amide-inducible aliphatic amidase operon. In the wild-type PAC1 strain, amidase expression is induced by acetamide or lactamide, but not by butyramide. A mutant strain of
Rajendra Singh et al.
Bioprocess and biosystems engineering, 41(8), 1225-1232 (2018-05-12)
Butyramide is a commodity chemical having wide range of applications from material science to biological sciences including synthesis of therapeutic drugs, hydroxamic acids, and electrorheological fluids. The nitrile hydratase protein of Bacillus sp. APB-6 was explored to develop an efficient
R A Norman et al.
The Journal of biological chemistry, 275(39), 30660-30667 (2000-07-13)
Expression of the amidase operon of Pseudomonas aeruginosa is controlled by AmiC, the ligand sensor and negative regulator, and AmiR the transcription antitermination factor activator. We have titrated out AmiC repression activity in vivo by increased AmiR production in trans
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