247588

Salicylsäure

ACS reagent, ≥99.0%

• Synonym(e): 2-Hydroxybenzoesäure
• Lineare Formel: 2^-(HO)C₆H₄CO₂H
• CAS-Nummer: 69-72-7
• Molekulargewicht: 138.12
• Beilstein: 774890
• EG-Nummer: 200-712-3
• MDL-Nummer: MFCD00002439
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24854876
• NACRES: NA.21

Eigenschaften

• Qualität: ACS reagent
• Qualitätsniveau: 200
• Dampfdichte: 4.8 (vs air)
• Dampfdruck: 1 mmHg ( 114 °C)
• Assay: ≥99.0%
• Verunreinigungen: H₂SO₄, passes test (darkened)
• Glührückstand: ≤0.01%
• bp: 211 °C (lit.)
• mp (Schmelzpunkt): 158-161 °C (lit.)
• Anionenspuren: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• Kationenspuren: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• SMILES String: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Angaben zum Gen: human ... ALB(213) , PTPN1(5770)

Beschreibung

Allgemeine Beschreibung

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Anwendung

Salicylic acid has been used:

• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Biochem./physiol. Wirkung

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H318,H361d
• P-Sätze: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): 314.6 °F - closed cup
• Flammpunkt (°C): 157 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves