142662

Chlorsulfonylisocyanat

98%

• Synonym(e): N-Carbonylsulfamylchlorid, CSI
• Lineare Formel: ClSO₂NCO
• CAS-Nummer: 1189-71-5
• Molekulargewicht: 141.53
• Beilstein: 1237247
• EG-Nummer: 214-715-2
• MDL-Nummer: MFCD00011608
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848531
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 5.57 psi ( 20 °C)
• Qualitätsniveau: 200
• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.447 (lit.)
• bp: 107 °C (lit.)
• mp (Schmelzpunkt): −44 °C (lit.)
• Dichte: 1.626 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: ClS(=O)(=O)N=C=O
• InChI: 1S/CClNO3S/c2-7(5,6)3-1-4
• InChIKey: WRJWRGBVPUUDLA-UHFFFAOYSA-N
• Angaben zum Gen: human ... ABCB1(5243) , FPR1(2357)

Beschreibung

Allgemeine Beschreibung

Chlorosulfonyl isocyanate is classified as an isocyanate and is widely used as a reagent in sulfonylation and carbamoylation reactions.Chlorosulfonyl isocyanate reacts with hydrocarbon alkenes via stepwise dipolar pathway to give N-chlorosulfonyl-β-lactams.

Anwendung

Employed in a regio- and diastereoselective introduction of a protected amino group in a synthesis of chiral, polyhydroxylated piperidines. Generation of ureas from amino groups in a synthesis of benzimidazolones.

Synthetically versatile reagent for the preparation of amides, lactams, and triazocinones.

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H314,H317,H334
• P-Sätze: P261 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Zusätzliche Gefahrenhinweise: EUH014
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): >230.0 °F
• Flammpunkt (°C): > 110 °C
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter