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Key Documents

1711268

USP

Venlafaxine

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

(+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor

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About This Item

Formula empirica (notazione di Hill):
C17H27NO2 Ā· HCl
Numero CAS:
Peso molecolare:
313.86
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

venlafaxine

Produttore/marchio commerciale

USP

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2

InChI

1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
QYRYFNHXARDNFZ-UHFFFAOYSA-N

Informazioni sul gene

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Venlafaxine hydrochloride USP reference standard intended for use in specified quality tests and assays.

Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):
  • Venlafaxine Hydrochloride
  • Venlafaxine Tablets
  • Venlafaxine Hydrochloride Extended-Release Capsules
  • Desvenlafaxine

Azioni biochim/fisiol

Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or Ī±-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.Ā Ā ā€‹

Altre note

Sales restrictions may apply.

Pittogrammi

Environment

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Aquatic Chronic 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolositĆ  dell'acqua (WGK)

WGK 3

Punto dā€™infiammabilitĆ  (Ā°F)

Not applicable

Punto dā€™infiammabilitĆ  (Ā°C)

Not applicable


Certificati d'analisi (COA)

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Desvenlafaxine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(5), 1280-1280 (2020)
R L Rudolph et al.
Journal of clinical psychopharmacology, 16(3 Suppl 2), 54S-59S (1996-06-01)
The tolerability and safety of venlafaxine hydrochloride, a new serotonin and norepinephrine reuptake inhibitor, are reviewed in this article. The data presented here are based on a pool of 3,082 patients who were treated with this agent during clinical trials.
Denise G Tate et al.
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The American journal of psychiatry, 171(8), 890-890 (2014-08-02)
C Reichert et al.
Clinical toxicology (Philadelphia, Pa.), 52(6), 629-634 (2014-05-23)
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