1414003

Methotrexate

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: (+)-Amethopterin, 4-Amino-10-methylfolic acid, 4-Amino-N¹⁰-methylpteroyl-L-glutamic acid, Antifolan, MTX, Methylaminopterin
• Formula empirica (notazione di Hill): C₂₀H₂₂N₈O₅
• Numero CAS: 59-05-2
• Peso molecolare: 454.44
• Beilstein: 70669
• Numero MDL: MFCD00064370
• Codice UNSPSC: 41116107
• ID PubChem: 329750410
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: methotrexate
• Produttore/marchio commerciale: USP
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1; FBOZXECLQNJBKD-ZDUSSCGKSA-N
• Informazioni sul gene: human ... DHFR(1719)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Methotrexate USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Methotrexate Injection
• Methotrexate Tablets
• Methotrexate for Injection

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H341,H360D,H372
• Consigli di prudenza: P202 - P260 - P264 - P280 - P301 + P310 - P405
• Classi di pericolo: Acute Tox. 3 Oral - Muta. 2 - Repr. 1B - STOT RE 1
• Organi bersaglio: Liver,Bone marrow
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable