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1260001

USP

Ethinyl estradiol

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

Ethinylestradiol

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About This Item

Formula empirica (notazione di Hill):
C20H24O2
Numero CAS:
57-63-6
Peso molecolare:
296.40
Beilstein:
2419975
Numero MDL:
MFCD00003690
Codice UNSPSC:
41116107
ID PubChem:
329749765
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

ethinyl estradiol

Produttore/marchio commerciale

USP

Punto di fusione

182-183 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc4cc(O)ccc24

InChI

1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1
BFPYWIDHMRZLRN-SLHNCBLASA-N

Informazioni sul gene

human ... ESR1(2099)

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Ethinyl estradiol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Desogestrel and Ethinyl Estradiol Tablets
  • Drospirenone and Ethinyl Estradiol Tablets
  • Ethinyl Estradiol
  • Ethinyl Estradiol Tablets
  • Ethynodiol Diacetate and Ethinyl Estradiol Tablets
  • Levonorgestrel and Ethinyl Estradiol Tablets
  • Norethindrone Acetate and Ethinyl Estradiol Tablets

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Avvertenze

Danger

Indicazioni di pericolo

H302,H351,H360Fd,H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 2 - Repr. 1A

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number

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Supelco

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Sigma-Aldrich

SML0147

Drospirenone

Lisa Baumann et al.
Toxicology and applied pharmacology, 278(3), 230-237 (2014-05-17)
The aim of the present study was to investigate the persistence of the feminizing effects of discontinued 17α-ethinylestradiol (EE2) exposure on zebrafish (Danio rerio). An exposure scenario covering the sensitive phase of sexual differentiation, as well as final gonad maturation
Jeremy A Leonard et al.
Aquatic toxicology (Amsterdam, Netherlands), 150, 103-116 (2014-03-29)
The endocrine disrupting effects of estrogenic compounds in surface waters on fish, such as feminization of males and altered sex ratios, may also occur in aquatic invertebrates. However, the underlying mechanisms of action and toxicity, especially in native freshwater mussels
Andrew M Kaunitz et al.
Obstetrics and gynecology, 123(2 Pt 1), 295-303 (2014-01-10)
To compare a new low-dose levonorgestrel and ethinyl estradiol contraceptive patch (Patch) with a combination oral contraceptive (Pill; 100 micrograms levonorgestrel, 20 micrograms ethinyl estradiol) regarding efficacy, safety, compliance, and unscheduled uterine bleeding. Women (17-40 years; body mass index 16-60)
Per Hallgren et al.
Environmental toxicology and chemistry, 33(4), 930-936 (2014-03-13)
Endocrine-disrupting chemicals are known to alter the fitness of individual organisms via changes in growth, behavior, and reproduction. It is largely unknown, however, whether these effects cascade through the food web and indirectly affect other, less sensitive organisms. The authors
Tomás Cajthaml et al.
Environmental pollution (Barking, Essex : 1987), 157(12), 3325-3335 (2009-07-25)
Natural estrogens such as estrone, 17beta-estradiol, estriol, and the particularly recalcitrant synthetic estrogen 17alpha-ethinylestradiol used as oral contraceptive, accumulate in the environment and may give rise to health problems. The processes participating in their removal from soil, wastewater, water-sediments, groundwater-aquifer
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