BP1225

Tamoxifen citrate

British Pharmacopoeia (BP) Reference Standard

• Sinonimo/i: Tamoxifen citrate salt, (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
• Formula empirica (notazione di Hill): C₂₆H₂₉NO · C₆H₈O₇
• Numero CAS: 54965-24-1
• Peso molecolare: 563.64
• Numero MDL: MFCD00058321
• Codice UNSPSC: 41116107

Proprietà

• Grado: pharmaceutical primary standard
• Livello qualitativo: 100
• Famiglia di API: tamoxifen
• Stato: solid
• Durata: limited shelf life, expiry date on the label
• Produttore/marchio commerciale: BP
• applicazioni: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: OC(=O)CC(O)(CC(O)=O)C(O)=O.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCN(C)C)cc3
• InChI: 1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;; FQZYTYWMLGAPFJ-OQKDUQJOSA-N
• Informazioni sul gene: human ... ESR1(2099)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Tamoxifen citrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tamoxifen Oral Solution

Tamoxifen Tablets

Azioni biochim/fisiol

Estrogen antagonist in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor.

Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Confezionamento

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H350,H360D,H410
• Consigli di prudenza: P201 - P273 - P301 + P312 + P330 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable