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73035AST

Supelco

Astec® CHIRALDEX G-TA Capillary GC Column

L × I.D. 50 m × 0.25 mm, df 0.12 μm

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About This Item

Codice UNSPSC:
41115710
NACRES:
SB.54

Materiali

fused silica

Livello qualitativo

Descrizione

GC capillary column

Confezionamento

pkg of 1 ea

Parametri

-10-180 °C temperature (isothermal or programmed)

Beta

500

df

0.12 μm

tecniche

gas chromatography (GC): suitable

Lungh. × D.I.

50 m × 0.25 mm

Gruppo funzionale matrice

non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of γ-cyclodextrin phase

applicazioni

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
life science and biopharma
personal care
pharmaceutical (small molecule)

Tipo di colonna

capillary chiral

Tecnica di separazione

chiral

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Descrizione generale

Astec® CHIRALDEX G-TA is the first choice in the Group 1 CSPs (Surface Interactions, Complex Derivatives). This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials. Separations occur without the inclusion mechanism and are typically faster and more efficient than most chiral stationary phases. G-TA has also been used to separate parent drug enantiomers and their metabolites. G-TA has its highest selectivity for oxygen-containing analytes like alcohols, diols and polyols as the free alcohol and as an acyl derivative; amines as acyl derivatives; amino alcohols, halogens (Cl>Br>F), amino acids, hydroxy acids, lactones, furans and pyrans. It is also highly selective for halogenated compounds.

Applicazioni


  • Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation. Application to enzymatic reactions.: This study explores the use of the Astec CHIRALDEX G-TA Capillary GC Column for enantioselective gas chromatographic analysis. The method involves on-line derivatization, enabling the analysis of aqueous samples and applying this technique to enzymatic reactions. This innovative approach highlights the column′s capability in achieving high selectivity and sensitivity for chiral compounds in complex matrices (Mommers et al., 2008).

Resistenza chim/fis

Temp. Limits:
  • -10 °C to 180 °C isothermal and programmed

Altre note

We offer a variety of chromatography accessories including analytical syringes

Note legali

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIRALDEX is a trademark of Sigma-Aldrich Co. LLC

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Catalytic asymmetric synthesis of Japonilure and its enantiomer
Xu, Hao, et al.
Tetrahedron Asymmetry, 25 (20-21), 1372-1375 (2014)
Investigation of a novel diamine based chiral auxiliary in the asymmetric alkylation of ketones
Clarke, Sarah L, et al.
Tetrahedron Asymmetry, 25 (4), 356-361 (2014)
Sequential kinetic resolution of (?)-2,3-butanediol in organic solvent using lipase from Pseudomonas cepacia.
Caron, Gaetan; Kazlauskas, R.J.
Tetrahedron Asymmetry, 4 (9), 1995-2000 (1993)
Asymmetric epoxidation catalyzed by esters of a-hydroxy-8-oxabicyclo[3.2.1]octan-3-one
Armstrong, A., et al.
Tetrahedron Asymmetry, 12 (20), 2779-2781 (2001)
Asymmetric ring opening of meso-epoxides with B-halobis(2-isocaranyl)boranes 2-dIcr2BX
Roy, Chandra D., Brown, Herbert C.
Tetrahedron Asymmetry, 17 (13), 1931-1936 (2006)

Articoli

Amino acids are building blocks of peptides and proteins. Enantiomeric separation of these molecules can be performed through chromatography by chiral stationary phases. This article describes the chiral GC analysis of one amino acid, proline, after achiral derivatization.

In this study we demonstrate the separation of D- and L-carvone enantiomers in samples of caraway seed, dill seed, native spearmint and scotch spearmint essential oils using an Astec CHIRALDEX G-TA capillary GC column.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.