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569253-U

Supelco

Discovery® HS C18 (3 µm) HPLC Columns

L × I.D. 5 cm × 2.1 mm, HPLC Column

Sinonimo/i:

Discovery RP18 HPLC Column

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About This Item

Codice UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

Nome del prodotto

Colonna HPLC Discovery® HS C18, 3 μm particle size, L × I.D. 5 cm × 2.1 mm

Materiali

stainless steel column

agenzia

suitable for USP L1

Nome Commerciale

Discovery®

Caratteristiche

endcapped

Produttore/marchio commerciale

Discovery®

Confezionamento

1 ea of

Grado di funzionalizzazione

20% Carbon loading

Parametri

≤70 °C temp. range
400 bar pressure (5801 psi)

tecniche

HPLC: suitable
LC/MS: suitable

Lungh. × D.I.

5 cm × 2.1 mm

Area superficiale

300 m2/g

Copertura della superficie

3.2 μmol/m2

Impurezze

<10 ppm metals

Matrice

silica gel, high purity, spherical particle platform
fully porous particle

Gruppo funzionale matrice

C18 (octadecyl) phase

Dimensione particelle

3 μm

Dimensione pori

120 Å

Intervallo di pH d’impiego

2-8

applicazioni

food and beverages

Tecnica di separazione

reversed phase

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Descrizione generale

Discovery® HS C18 HPLC column (L × I.D. 5 cm × 2.1 mm) is commonly found to be stable under acidic and basic conditions.

Applicazioni


  • Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).

  • A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).

  • Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).

Caratteristiche e vantaggi

  • Stabile, a bassa perdita per applicazioni LC-MS
  • Scalabile dalla colonna analitica alla preparatoria
  • Molto stabile per garantire una eccellente riproducibilità da un ciclo all′altro e da un lotto all′altro
  • Maggiore idrofobia per una migliore risoluzione degli analiti difficili
   

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Note legali

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

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