53591-U

Ascentis^® Express 90 Å F5 (2.7 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

• Sinonimo/i: Core-shell (SPP) Fused Core PFP HPLC column
• Codice UNSPSC: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Proprietà

• Nome del prodotto: Ascentis^® Express F5, 2.7 μm HPLC Column, 2.7 μm particle size, L × I.D. 15 cm × 4.6 mm
• Materiali: stainless steel column
• Livello qualitativo: 100
• agenzia: suitable for USP L43
• Nome Commerciale: Ascentis^®
• Caratteristiche: endcapped
• Produttore/marchio commerciale: Ascentis^®
• Confezionamento: 1 ea of
• Parametri: 60 °C temp. range; 600 bar max. pressure (9000 psi)
• tecniche: HPLC: suitable; LC/MS: suitable; UHPLC-MS: suitable; UHPLC: suitable
• Lungh. × D.I.: 15 cm × 4.6 mm
• Area superficiale: 135 m²/g
• Impurezze: <5 ppm metals
• Matrice: Fused-Core particle platform; superficially porous particle
• Gruppo funzionale matrice: PFP (pentafluorophenyl) phase
• Dimensione particelle: 2.7 μm
• Dimensione pori: 90 Å pore size
• pH di lavoro: 2-8
• applicazioni: food and beverages
• Tecnica di separazione: reversed phase

Descrizione

Descrizione generale

The pentafluorophenylpropyl stationary phase of Ascentis Express F5 provides a stable reversed phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines.In addition to forming pi-pi and mildly steric interactions, F5 phases also retain compounds by polar interactions. Ascentis Express F5 can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.

Applicazioni

• Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry.: This study demonstrates the use of high-performance liquid chromatography (HPLC) with ion trap time-of-flight mass spectrometry for the determination of lumacaftor in the presence of ivacaftor. The research identifies five novel degradation products, showcasing the advanced analytical capabilities of the Ascentis^® Express F5, 2.7 µm HPLC Column for complex mixtures and degradation studies (Özcan et al., 2023).


• Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product.: This paper details the development of stability-indicating methods using LC-MS/MS and LC-DAD for the determination of tasimelteon. It highlights the robustness and sensitivity of these methods in identifying novel degradation products, with the Ascentis^® Express F5 column playing a crucial role in separation efficiency and stability analysis (Özcan et al., 2020).


• Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review article discusses recent advancements in ultra-fast HPLC, focusing on new generation superficially porous silica columns, including the Ascentis^® Express F5, 2.7 µm HPLC Column. It provides insights into the enhanced performance, speed, and efficiency of these columns in high-throughput analytical applications (Ali et al., 2012).

Note legali

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable