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Key Documents

Altri documenti

T6901

Sigma-Aldrich

α1-Mating Factor acetate salt

≥93% (HPLC), synthetic

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About This Item

Formula empirica (notazione di Hill):
C82H114N20O17S
Numero CAS:
59401-28-4
Peso molecolare:
1683.97
Numero MDL:
MFCD00133883
Codice UNSPSC:
51111800
ID PubChem:
24900413
NACRES:
NA.32

Origine biologica

synthetic

Livello qualitativo

200

Saggio

≥93% (HPLC)

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Temperatura di conservazione

−20°C

Stringa SMILE

CSCCC(NC(=O)C1CCCN1C(=O)C(CCC(N)=O)NC(=O)CNC(=O)C2CCCN2C(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc3c[nH]c4ccccc34)NC(=O)C(Cc5cnc[nH]5)NC(=O)C(N)Cc6c[nH]c7ccccc67)C(=O)NC(Cc8ccc(O)cc8)C(O)=O

InChI

1S/C82H114N20O17S/c1-45(2)34-61(98-76(112)63(38-49-41-89-56-17-9-7-15-53(49)56)99-77(113)64(39-50-42-87-44-91-50)96-71(107)54(84)37-48-40-88-55-16-8-6-14-52(48)55)74(110)93-57(25-27-68(85)104)72(108)97-62(35-46(3)4)75(111)95-59(18-10-11-30-83)80(116)101-31-12-19-66(101)78(114)90-43-70(106)92-60(26-28-69(86)105)81(117)102-32-13-20-67(102)79(115)94-58(29-33-120-5)73(109)100-65(82(118)119)36-47-21-23-51(103)24-22-47/h6-9,14-17,21-24,40-42,44-46,54,57-67,88-89,103H,10-13,18-20,25-39,43,83-84H2,1-5H3,(H2,85,104)(H2,86,105)(H,87,91)(H,90,114)(H,92,106)(H,93,110)(H,94,115)(H,95,111)(H,96,107)(H,97,108)(H,98,112)(H,99,113)(H,100,109)(H,118,119)
SBKVPJHMSUXZTA-UHFFFAOYSA-N

Amino Acid Sequence

Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

Applicazioni

α1-Mating Factor acetate salt has been used for the synchronization of yeast cells for flow cytometry and to study B-type cyclin (Clb2p)-EmCitrine levels from calcofluor white treated cells.

Azioni biochim/fisiol

The α1-Mating factor is a pheromone produced by yeast that regulates mating. α1-Mating Factor acetate salt can be utilized to arrest the G1-phase of the cell cycle in various yeast strains.

Nota sulla preparazione

Alpha1-Mating Factor acetate salt dissolves in water at 1 mg/ml to yield a clear, colorless solution.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Mingliang Zhang et al.
Eukaryotic cell, 1(5), 811-822 (2002-11-29)
Fungal adhesins represent a large family of serine/threonine-rich secreted glycoproteins. Adhesins have been shown to play roles in heterotypic and homotypic cell-cell adhesion processes, morphogenetic pathways and invasive/pseudohyphal growth, frequently in response to differentiation cues. Here we address the role
Stefano Vernarecci et al.
Molecular and cellular biology, 28(3), 988-996 (2007-11-28)
We report that the histone acetyltransferase Gcn5p is involved in cell cycle progression, whereas its absence induces several mitotic defects, including inefficient nuclear division, chromosome loss, delayed G(2) progression, and spindle elongation. The fidelity of chromosome segregation is finely regulated
Oliver Kerscher et al.
Molecular and cellular biology, 23(18), 6406-6418 (2003-08-29)
Spindle checkpoint proteins monitor the interaction of the spindle apparatus with the kinetochores, halting anaphase even if the microtubule attachment of only a single chromosome is altered. In this study, we show that Bub3p of Saccharomyces cerevisiae, an evolutionarily conserved
C Formosa et al.
Journal of molecular recognition : JMR, 28(1), 1-9 (2015-06-06)
Single-molecule force spectroscopy using atomic force microscopy (AFM) is more and more used to detect and map receptors, enzymes, adhesins, or any other molecules at the surface of living cells. To be specific, this technique requires antibodies or ligands covalently
Fozia Akhtar et al.
International journal of molecular sciences, 24(3) (2023-02-12)
Mnemons are prion-like elements that encode cellular memories of past cellular adaptations and do not spread to progenies during cell divisions. During the deceptive courtship in budding yeast, the Whi3 mnemon (Whi3mnem) condenses into a super-assembly to encode a mating
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