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T3165

Sigma-Aldrich

7-Methoxy-4-(trifluoromethyl)coumarin

≥99% (TLC)

Sinonimo/i:

Methyl 4-(trifluoromethyl)umbelliferyl ether

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About This Item

Formula empirica (notazione di Hill):
C11H7F3O3
Numero CAS:
575-04-2
Peso molecolare:
244.17
Beilstein:
225039
Numero MDL:
MFCD00132980
Codice UNSPSC:
12352204
ID PubChem:
24900113
NACRES:
NA.32

Saggio

≥99% (TLC)

Forma fisica

powder

Solubilità

acetone: 50 mg/mL, clear, colorless to faintly yellow

Fluorescenza

λex 333 nm; λem 416 nm in methanol

Stringa SMILE

COc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C11H7F3O3/c1-16-6-2-3-7-8(11(12,13)14)5-10(15)17-9(7)4-6/h2-5H,1H3
HAZHUELNIGDYQH-UHFFFAOYSA-N

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Applicazioni

7-Methoxy-4-(trifluoromethyl)coumarin has been used as a substrate in cytochrome P450 2E1 (CYP2E1) activity assay and aromatase assay.

Azioni biochim/fisiol

The enzymatic action of cytochrome P450 2E1 (CYP2E1) on 7-methoxy-4-(trifluoromethyl)coumarin results in a fluorescent product 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) that can be measured at 409/530 nm.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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