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T2501

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

≥98% (HPLC), powder

Sinonimo/i:

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

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About This Item

Formula condensata:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Numero CAS:
6106-07-6
Peso molecolare:
888.93
Beilstein:
5721845
Numero CE:
200-221-4
Numero MDL:
MFCD00149110
Codice UNSPSC:
51111800
ID PubChem:
24900041
NACRES:
NA.32

Origine biologica

synthetic (organic)

Sterilità

non-sterile

Saggio

≥98% (HPLC)

Forma fisica

powder

Punto di fusione

207-210 (dec.) (lit.)

Solubilità

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

Stringa SMILE

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1
JMHCCAYJTTWMCX-QWPJCUCISA-M

Informazioni sul gene

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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Azioni biochim/fisiol

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Nota sulla preparazione

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H372

Classi di pericolo

STOT RE 1

Organi bersaglio

Thyroid,Cardio-vascular system,Kidney

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Sigma-Aldrich

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Sigma-Aldrich

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