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T0397

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

γ-irradiated, powder, BioXtra, suitable for cell culture

Sinonimo/i:

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

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About This Item

Formula condensata:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Numero CAS:
6106-07-6
Peso molecolare:
888.93
Beilstein:
5721845
Numero CE:
200-221-4
Numero MDL:
MFCD00149110
Codice UNSPSC:
12352209
ID PubChem:
24899887
NACRES:
NA.77

Origine biologica

synthetic (organic)

Livello qualitativo

200

Sterilità

γ-irradiated

Nome Commerciale

BioXtra

Saggio

≥98%

Forma fisica

powder

Potenza

5-50 ng/mL

tecniche

cell culture | mammalian: suitable

Punto di fusione

207-210 (dec.) (lit.)

Solubilità

cell culture medium: 0.1 mg/mL
H2O: soluble

Temperatura di conservazione

−20°C

Stringa SMILE

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1
JMHCCAYJTTWMCX-QWPJCUCISA-M

Informazioni sul gene

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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Categorie correlate

Azioni biochim/fisiol

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Stato fisico

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

Ricostituzione

To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H372

Classi di pericolo

STOT RE 1

Organi bersaglio

Thyroid,Cardio-vascular system,Kidney

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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