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Key Documents

SRP3253

Sigma-Aldrich

SDF-1 beta from rat

≥95%(SDS-PAGE & HPLC), recombinant, expressed in E. coli, lyophilized, suitable for cell culture

Sinonimo/i:

CXCL12, PBSF, Stromal-Cell Derived Factor-1

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About This Item

Codice UNSPSC:
12352202
NACRES:
NA.32

product name

SDF-1 beta from rat, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

Origine biologica

rat

Ricombinante

expressed in E. coli

Saggio

≥95% (HPLC)
≥95% (SDS-PAGE)

Forma fisica

lyophilized

Potenza

100.0-200.0 ng/mL

PM

8.4 kDa

Confezionamento

pkg of 10 μg

tecniche

cell culture | mammalian: suitable

Impurezze

<0.1 EU/μg endotoxin, tested

Colore

yellow-white

N° accesso UniProt

Q9QZD1

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

rat ... CXCL12(24772)

Descrizione generale

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1b is an 8.4 kDa protein containing 72 amino acid residues.

Azioni biochim/fisiol

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. Recombinant rat SDF-1b is an 8.4 kDa protein containing 72 amino acid residues.

Sequenza

KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

Stato fisico

Lyophilized with no additives.

Ricostituzione

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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M D'Apuzzo et al.
European journal of immunology, 27(7), 1788-1793 (1997-07-01)
In the bone marrow, progenitor (pro-) and precursor (pre-) B cells depend on close contact with stromal cells for growth and maturation. Stromal cell-derived factor 1 (SDF-1), also known as pre-B cell growth-stimulating factor, is produced by bone marrow stromal
E Oberlin et al.
Nature, 382(6594), 833-835 (1996-08-29)
A putative chemokine receptor that we previously cloned and termed LESTR has recently been shown to function as a co-receptor (termed fusin) for lymphocyte-tropic HIV-1 strains. Cells expressing CD4 became permissive to infection with T-cell-line-adapted HIV-1 strains of the syncytium-inducing

Articoli

Injectable Hydrogels for Cell Delivery and Tissue Regeneration

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

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