SML3688

Hypoxia probe 4

≥95% (HPLC)

• Sinonimo/i: 5-Methoxy-1,2-dimethyl-3-(((3-oxo-9-(O-tolyl)-3H-xanthen-6-yl)oxy)methyl)-1H-indole-4,7-dione
• Formula empirica (notazione di Hill): C₃₂H₂₅NO₆
• Peso molecolare: 519.54
• Codice UNSPSC: 41116158
• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Stato: powder
• Condizioni di stoccaggio: protect from light
• Colore: , Faint yellow to yellow-brown
• Solubilità: DMSO: 2 mg/mL, clear
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: -10 to -25°C
• Stringa SMILE: CN1C(C(C=C2OC)=O)=C(C2=O)C(COC3=CC=C(C(C4=CC=CC=C4C)=C5C=C6)C(OC5=CC6=O)=C3)=C1C
• InChI: 1S/C32H25NO6/c1-17-7-5-6-8-21(17)29-22-11-9-19(34)13-26(22)39-27-14-20(10-12-23(27)29)38-16-24-18(2)33(3)31-25(35)15-28(37-4)32(36)30(24)31/h5-15H,16H2,1-4H3; MQKQLIOGOATWPT-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

Hypoxia probe 4 is a Tokyo green-based non-fluorescent hypoxia probe that undergoes cytochrome P450 reductase (PH51)-catalyzed reduction to yield the fluorescent reporter Tokyo green (ex 480 nm, em 515 nm) in conditions of 0.5% O2 and lower, allowing imaging hypoxia levels similar to those detected by EF5 without the use of antibodies. When employed together with resorufin-based hypoxia probe 2 (ex 545 nm, em 582 nm), the probe pair allows the simultaneous (two-color) imaging of different hypoxia levels in living cells.

Tokyo green-based hypoxia probe that allows fluorescent imaging of hypoxia levels in live cells similar to those detected by EF5 without the use of antibodies.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable