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SML2485

Sigma-Aldrich

Marbofloxacin

≥98% (HPLC)

Sinonimo/i:

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic acid, Aurizon, Marbocyl, Zeniquin, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid, Zeniquin®

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About This Item

Formula empirica (notazione di Hill):
C17H19FN4O4
Numero CAS:
115550-35-1
Peso molecolare:
362.36
Numero MDL:
MFCD00864820
Codice UNSPSC:
12352200
NACRES:
NA.77

Saggio

≥98% (HPLC)

Stato

powder

Colore

white to beige

Solubilità

DMSO: 2 mg/mL, clear (warmed)

Temperatura di conservazione

2-8°C

Stringa SMILE

CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O

InChI

1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
BPFYOAJNDMUVBL-UHFFFAOYSA-N

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Azioni biochim/fisiol

Marbofloxacin is a broad-spectrum fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria. It is believed to act by impairing the bacterial DNA gyrase. Marbofloxacin has also been shown to exhibit antileishmanial activity in a canine model.

Note legali

Zeniquin is a registered trademark of Pfizer, Inc.

Indicazioni di pericolo

H412

Consigli di prudenza

P273 - P501

Classi di pericolo

Aquatic Chronic 3

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

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Certificati d'analisi (COA)

Lot/Batch Number

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Marilisa Novacco et al.
Veterinary microbiology, 217, 112-120 (2018-04-05)
Mycoplasma haemofelis is the most pathogenic feline hemoplasma species and a causative agent of infectious hemolytic anemia in cats. Current treatment protocols are effective in reducing M. haemofelis blood loads and clinical signs but consistent bacteremia clearance is rarely achieved.
Carmen Pineda et al.
PloS one, 12(10), e0185981-e0185981 (2017-10-06)
Treatment of canine leishmaniasis (CanL) represents a challenge. Due to the high prevalence of renal disease associated to CanL, it is important to find an effective drug that does not damage the kidneys. Marbofloxacin has been shown to be effective
M Spreng et al.
Journal of veterinary pharmacology and therapeutics, 18(4), 284-289 (1995-08-01)
Marbofloxacin is a new fluoroquinolone developed exclusively for veterinary use. Minimum inhibitory concentrations of marbofloxacin were assessed for 816 recent isolates associated with canine or feline diseases. Marbofloxacin showed a broad spectrum of activity against gram-negative and gram-positive bacteria. In

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