SML1606

Oseltamivir phosphate

≥98% (HPLC)

• Sinonimo/i: GS4104, (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester phosphate salt
• Formula empirica (notazione di Hill): C₁₆H₂₈N₂O₄ ·H₃PO₄
• Numero CAS: 204255-11-8
• Peso molecolare: 410.40
• Numero MDL: MFCD08059548
• Codice UNSPSC: 12352200
• ID PubChem: 329825492
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Forma fisica: powder
• Attività ottica: [α]/D -26 to -36°, c = 1 in H₂O
• Colore: white to beige
• Solubilità: H₂O: 30 mg/mL, clear
• Temperatura di conservazione: −20°C
• Stringa SMILE: OP(O)(O)=O.CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
• InChI: 1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/m0./s1; PGZUMBJQJWIWGJ-ONAKXNSWSA-N

Descrizione

Azioni biochim/fisiol

Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. Oseltamivir phosphate, an antiviral, is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. Oseltamivir phosphate is hydrolyzed in the liver to its active form, oseltamivir carboxylate, which is an inhibitor of influenza viral neuraminidases essential for viral replication. Oseltamivir has a broad spectrum of activity against a range of influenza A and B subtypes with IC₅₀ values for neuraminidases measured from less than 1 nM to approximately 30 nM, depending on the virus subtype.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317,H319,H412
• Consigli di prudenza: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable