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SML1016

Sigma-Aldrich

Camalexin

≥98% (HPLC)

Sinonimo/i:

3-(Thiazol-2-yl)-1H-indole, Camalexine

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About This Item

Formula empirica (notazione di Hill):
C11H8N2S
Numero CAS:
135531-86-1
Peso molecolare:
200.26
Numero MDL:
MFCD18451889
Codice UNSPSC:
12352200
ID PubChem:
329825632
NACRES:
NA.77

Saggio

≥98% (HPLC)

Forma fisica

powder

Colore

white to light brown

Solubilità

DMSO: 20 mg/mL, clear

Temperatura di conservazione

2-8°C

Stringa SMILE

C12=CC=CC=C1NC=C2C3=NC=CS3

InChI

1S/C11H8N2S/c1-2-4-10-8(3-1)9(7-13-10)11-12-5-6-14-11/h1-7,13H
IYODIJVWGPRBGQ-UHFFFAOYSA-N

Applicazioni

Camalexin has been used in quantification and tolerance assays in Arabidopsis thaliana leaves.

Azioni biochim/fisiol

Camalexin is a phytoalexin isolated from cruciferous plants that exhibits antibacterial, antifungal, antiproliferative and cancer chemopreventive activities. Apparently, camalexin increases the ROS levels and is more effective in aggressive prostate cancer cells that express high ROS levels. In Arabidopsis thaliana, camalexin and salicylic acid confer resistance to Phytophthora capsici.

Caratteristiche e vantaggi

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H315,H319,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Plant physiology, 176(1), 538-551 (2017-11-11)
Glutathione (GSH) and indole glucosinolates (IGs) exert key functions in the immune system of the model plant Arabidopsis (
Jhon Venegas-Molina et al.
Scientific reports, 10(1), 10319-10319 (2020-06-27)
The plant hormones salicylic acid (SA) and jasmonic acid (JA) regulate defense mechanisms capable of overcoming different plant stress conditions and constitute distinct but interconnected signaling pathways. Interestingly, several other molecules are reported to trigger stress-specific defense responses to biotic
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The association among environmental cues, ethylene response, ABA signaling, and reactive oxygen species (ROS) homeostasis in the process of seed dormancy release is nowadays well-established in many species. Alternating temperatures are recognized as one of the main environmental signals determining
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Plant defense often depends on the synthesis and targeted delivery of antimicrobial metabolites at pathogen contact sites. The pleiotropic drug resistance (PDR) transporter PENETRATION3 (PEN3)/PDR8 in Arabidopsis (Arabidopsis thaliana) has been implicated in resistance to a variety of fungal pathogens.
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