SMB01065

Neolicuroside

≥85% (LC/MS-ELSD)

• Sinonimo/i: 4-O-(beta-D-apiofuranosyl(1-2)-beta-D-glucopyranosyl)isoliquiritigenin, Isoliquiritigenin-4′-O-apiosyl(1→2)glucoside, Isoliquiritin apioside
• Formula empirica (notazione di Hill): C₂₆H₃₀O₁₃
• Numero CAS: 120926-46-7
• Peso molecolare: 550.51
• Numero MDL: MFCD20487832
• Codice UNSPSC: 12352205
• NACRES: NA.25

Proprietà

• Origine biologica: plant
• Saggio: ≥85% (LC/MS-ELSD)
• Stato: solid
• PM: 550.51
• Solubilità: water: slightly soluble
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: −20°C
• Stringa SMILE: O1[C@H]([C@@H]([C@@](C1)(O)CO)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)Oc3ccc(cc3)\C=C\C(=O)c4c(cc(cc4)O)O
• InChI: 1S/C26H30O13/c27-10-19-20(32)21(33)22(39-25-23(34)26(35,11-28)12-36-25)24(38-19)37-15-5-1-13(2-6-15)3-8-17(30)16-7-4-14(29)9-18(16)31/h1-9,19-25,27-29,31-35H,10-12H2/b8-3+/t19-,20-,21+,22-,23+,24-,25+,26-/m1/s1; VMMVZVPAYFZNBM-KVFWHIKKSA-N

Descrizione

Descrizione generale

Natural product derived from plant source.

Neolicuroside, also known as Isoliquiritin apioside, is a chalcone glycoside structurally related to steroidal saponins. This bioactive plant metabolite is commonly derived from the roots of Glycyrrhiza Sp. plants and has demonstrated anti-inflammatory, anti-tussive, anti-tumor, antigenotoxic(1), anti-diabetic, and antioxidant properties.

Applicazioni

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Azioni biochim/fisiol

Neolicuroside modulates signaling pathways (e.g., MAPK, NF-κB), impacting vital cell processes such as proliferation, differentiation, and apoptosis. Its multitargeted mechanism includes scavenging free radicals, suppressing pro-inflammatory cytokine production, inhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermore, it also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4).

Caratteristiche e vantaggi

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Altre note

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable