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Merck
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Documenti fondamentali

SAB5200006

Sigma-Aldrich

Monoclonal Anti-CRYAA antibody produced in mouse

clone 1H3.B8, 1 mg/mL, purified immunoglobulin

Sinonimo/i:

Anti-Acry1, Anti-Alpha A Crystallin, Anti-CRYA1, Anti-CRYAA, Anti-Heat Shock protein beta4, Anti-HspB4

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

1H3.B8, monoclonal

Forma fisica

buffered aqueous glycerol solution

PM

antigen predicted mol wt 20 kDa

Reattività contro le specie

bovine, rat, mouse, human

Concentrazione

1 mg/mL

tecniche

indirect ELISA: suitable
western blot: suitable

Isotipo

IgG1

N° accesso NCBI

NP_000385.1

N° accesso UniProt

P02489

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CRYAA(1409)

Specificità

Detects α-crystallin at ~20 kDa. Does not cross-react with αB-crystallin, βL-crystallin, βH- crystallin, γ-crystallin, Hsp25, Hsp27 or Hsp47 proteins.

Immunogeno

Native Alpha Crystallin

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in PBS, pH 7.2, in 50% glycerol, and 0.09% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Shiwani Sharma et al.
Molecular vision, 24, 801-817 (2019-02-05)
Pseudoexfoliation (PEX) syndrome is an age-related progressive disease of the extracellular matrix with ocular manifestations. PEX is clinically diagnosed by the presence of extracellular exfoliative deposits on the anterior surface of the ocular lens. PEX syndrome is a major risk
Xiang-Jia Zhu et al.
Journal of cellular and molecular medicine, 22(2), 1118-1126 (2017-10-11)
Post-translational modifications in lens proteins are key causal factors in cataract. As the most abundant post-translational modification in the lens, racemization may be closely related to the pathogenesis of cataract. Racemization of αA-crystallin, a crucial structural and heat shock protein
Andrea Schlotterer et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4141-4153 (2018-11-30)
The aim of this study was to evaluate whether damage to the neurovascular unit in diabetes depends on reactive metabolites such as methylglyoxal (MG), and to assess its impact on retinal gene expression. Male Wistar rats were supplied with MG
Jason Tchieu et al.
Cell stem cell, 21(3), 399-410 (2017-09-09)
Directing the fate of human pluripotent stem cells (hPSCs) into different lineages requires variable starting conditions and components with undefined activities, introducing inconsistencies that confound reproducibility and assessment of specific perturbations. Here we introduce a simple, modular protocol for deriving

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

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