SAB4702061

Monoclonal Anti-CD10 APC-Cyanine7 produced in mouse

• Sinonimo/i: Atriopeptidase, CALLA, Enkephalinase, MME, Neprilysin, Neutral endopeptidase
• Codice UNSPSC: 12352203

Proprietà

• Coniugato: APC-Cy7 conjugate
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: MEM-78, monoclonal
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• tecniche: flow cytometry: suitable
• Isotipo: IgG1
• N° accesso UniProt: P08473
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... MME(4311)

Descrizione

Descrizione generale

CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.

Specificità

The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

Immunogeno

NALM-6 human pre-B cell line

Stato fisico

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota sulla preparazione

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Stoccaggio e stabilità

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Altre note

The antibody solution should be gently mixed before use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable