SAB4504551

Anti-phospho-Synuclein-α (pTyr¹³³) antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41
• Clone: polyclonal
• application: ELISA; WB
• Reattività contro le specie: mouse, human, rat
• tecniche: ELISA: 1:40000; western blot: 1:500-1:1000
• citations: 3

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• PM: antigen 14 kDa
• Reattività contro le specie: mouse, human, rat
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:40000; western blot: 1:500-1:1000
• N° accesso NCBI: P37840
• N° accesso UniProt: P37840
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr133)
• Informazioni sul gene: human ... SNCA(6622)

Descrizione

Descrizione generale

The SNCA (synuclein α) gene codes for a 140-amino acid protein a-synuclein, that is mapped to human chromosome 4q21-23.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Tyr133.

Immunogen Range: 91-140

Azioni biochim/fisiol

Synuclein-α is known to induce oligodendrocyte maturation. Accumulation of α-synuclein in oligodendrocytes results in the loss of myelin and causes neurodegeneration, leading to multiple system atrophy. Mutations in the SNCA gene results in Parkinson′s disease.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable