SAB4500814

Anti-Estrogen Receptor-β antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: ESR2, ESTRB, Estrogen receptor β, NR3A2
• Numero MDL: MFCD01323253
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 59 kDa
• Reattività contro le specie: human, rat, mouse
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• N° accesso NCBI: Q92731
• N° accesso UniProt: Q92731
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ESR2(2100)

Descrizione

Descrizione generale

Estrogen Receptor-β (ERβ) is a member of the nuclear receptor superfamily. It has nine exons and is mapped to human chromosome 14q23.2.

Anti-Estrogen Receptor-β Antibody detects endogenous levels of total Estrogen Receptor-β protein.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-beta.

Immunogen Range: 71-120

Applicazioni

Anti-Estrogen Receptor-βantibody has been used in western blotting .{42,43}

Azioni biochim/fisiol

Estrogen Receptor-β (ERβ) is involved in immune and inflammatory response. In females, estrogen receptor β (ESR2) is expected to play an important role in the progress of MDD (major depressive disorder). Aberrations in ESR2 gene result in bone mineral density variation.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable