SAB4300684

Anti-phospho-Cyclin E1 (pThr³⁹⁵) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-CCNE, Anti-CCNE1
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~48 kDa
• Reattività contro le specie: human
• Concentrazione: 1 mg/mL
• tecniche: western blot: 1:500-1:1000
• Isotipo: IgG
• Sequenza immunogenica: (L-L-Tp-P-P)
• N° accesso NCBI: NM_001238.1
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pThr395)
• Informazioni sul gene: human ... CCNE1(898)

Descrizione

Descrizione generale

The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.

Immunogeno

Peptide sequence around phosphorylation site of threonine 395 (L-L-Tp-P-P), according to the protein NP_001229.1

Caratteristiche e vantaggi

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Descrizione del bersaglio

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable