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SAB3501078

Sigma-Aldrich

Anti-TMIGD1 antibody produced in rabbit

affinity isolated antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41
Coniugato:
unconjugated
application:
ELISA
Clone:
polyclonal
Reattività contro le specie:
rat, mouse, human
citations:
1
tecniche:
ELISA: suitable
immunoblotting: suitable

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

PM

predicted mol wt 29 kDa

Reattività contro le specie

rat, mouse, human

Concentrazione

1 mg/mL

tecniche

ELISA: suitable
immunoblotting: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... TMIGD1(388364)

Descrizione generale

TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is a novel adhesion molecule expressed in several organs and tissues, specifically in renal tubular epithelial cells. It is composed of two putative immunoglobulin domains, which mediates self-dimerization.

Immunogeno

Antibody was raised against an 18 amino acid peptide near the center of human TMIGD1.

Applicazioni

Anti-TMIGD1 antibody produced in rabbit is suitable for immunoblot and ELISA.

Azioni biochim/fisiol

TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is involved in various cellular processes such as regulation of cell structure, cell-cell adhesion, and cellular movement. Its extracellular domain stabilizes the cell morphology and cell-cell interaction. TMIGD1 plays an important role in cell survival by protecting it from oxidative cell injury. It protects cells from oxidative and nutrient-deprivation-induced cell injury by stabilizing the transepithelial electric resistance and permeability of renal epithelial cells.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3501078.

Stato fisico

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Koji Fujimoto et al.
Gastroenterology, 123(6), 1941-1948 (2002-11-28)
The surface epithelium of the colon is being replaced constantly with cells derived from the stem cells of the crypt. Although the location of the stem cells is known, there are no markers for these cells. This study tested the
Junli Yan et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(6), 1841-1846 (2007-02-01)
Tight regulation of p53 is essential for maintaining normal cell growth. Here we report that BLIMP1 acts in an autoregulatory feedback loop that controls p53 activity through repression of p53 transcription. p53 binds to and positively regulates BLIMP1, which encodes
Elisa Cattaneo et al.
EMBO molecular medicine, 3(6), 334-347 (2011-05-04)
Improved colonoscopy is revealing precancerous lesions that were frequently missed in the past, and ∼30% of those detected today have nonpolypoid morphologies ranging from slightly raised to depressed. To characterize these lesions molecularly, we assessed transcription of 23,768 genes in
Emad Arafa et al.
The American journal of pathology, 185(10), 2757-2767 (2015-09-08)
Oxidative damage to renal tubular epithelial cells is a fundamental pathogenic mechanism implicated in both acute kidney injury and chronic kidney diseases. Because epithelial cell survival influences the outcome of acute kidney injury and chronic kidney diseases, identifying its molecular
Hilary F Clark et al.
Genome research, 13(10), 2265-2270 (2003-09-17)
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to identify cDNA clones encoding

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